Plague (disease) in the context of "Thucydides"

Apollo is one of the Olympian deities in ancient Greek and Roman religion, as well as Greek and Roman mythology. Apollo has been recognized as a god of archery, music and dance, truth and prophecy, healing and diseases, the Sun and light, poetry, and more. One of the most important and complex of the Greek gods, he is the son of Zeus and Leto, and the twin brother of Artemis, goddess of the hunt. He is considered to be the most beautiful god and is represented as the ideal of the kouros (ephebe, or a beardless, athletic youth). Apollo is known in Greek-influenced Etruscan mythology as Apulu.

As the patron deity of Delphi (Apollo Pythios), Apollo is an oracular god—the prophetic deity of the Delphic Oracle and the deity of ritual purification. His oracles were often consulted for guidance in various matters. He was in general seen as the god who affords help and wards off evil, and is referred to as Alexicacus, the "averter of evil". Medicine and healing are associated with Apollo, whether through the god himself or mediated through his son Asclepius. Apollo delivered people from epidemics, yet he is also a god who could bring ill health and deadly plague with his arrows. The invention of archery itself is credited to Apollo and his sister Artemis. Apollo is usually described as carrying a silver or golden bow and a quiver of arrows.

The late Middle Ages or late medieval period was the period of European history lasting from 1300 to 1500 AD. The late Middle Ages followed the High Middle Ages and preceded the onset of the early modern period (and in much of Europe, the Renaissance).

Around 1350, centuries of prosperity and growth in Europe came to a halt. A series of famines and plagues, including the Great Famine of 1315–1317 and the Black Death, reduced the population to around half of what it had been before the calamities. Along with depopulation came social unrest and endemic warfare. France and England experienced serious peasant uprisings, such as the Jacquerie and the Peasants' Revolt, as well as over a century of intermittent conflict, the Hundred Years' War. To add to the many problems of the period, the unity of the Catholic Church was temporarily shattered by the Western Schism. Collectively, those events are sometimes called the crisis of the late Middle Ages.

Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. One to seven days after exposure to the bacteria, flu-like symptoms develop. These symptoms include fever, headaches, and vomiting, as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. Acral necrosis, the dark discoloration of skin, is another symptom. Occasionally, swollen lymph nodes, known as "buboes", may break open.

The three types of plague are the result of the route of infection: bubonic plague, septicemic plague, and pneumonic plague. Bubonic plague is mainly spread by infected fleas from small animals. It may also result from exposure to the body fluids from a dead plague-infected animal. Mammals such as rabbits, hares, and some cat species are susceptible to bubonic plague, and typically die upon contraction. In the bubonic form of plague, the bacteria enter through the skin through a flea bite and travel via the lymphatic vessels to a lymph node, causing it to swell. Diagnosis is made by finding the bacteria in the blood, sputum, or fluid from lymph nodes.

A pandemic (/pænˈdɛmɪk/ pan-DEM-ik) is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial portion of the human population. Widespread endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide.

Throughout human history, there have been a number of pandemics of diseases such as smallpox. The Black Death, caused by the Plague, caused the deaths of up to half of the population of Europe in the 14th century. The term pandemic had not been used then, but was used for later epidemics, including the 1918 H1N1 influenza A pandemic—more commonly known as the Spanish flu—which is the deadliest pandemic in history. The most recent pandemics include the HIV/AIDS pandemic, the 2009 swine flu pandemic and the COVID-19 pandemic. Almost all these diseases still circulate among humans though their impact now is often far less.

Yersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores. It is related to pathogens Yersinia enterocolitica, and Yersinia pseudotuberculosis, from which it evolved. Yersinia pestis is responsible for the disease plague, which caused the Plague of Justinian and the Black Death, one of the deadliest pandemics in recorded history. Plague takes three main forms: pneumonic, septicemic, and bubonic. Y. pestis is a facultative anaerobic parasitic bacterium that can infect humans primarily via its host the Oriental rat flea (Xenopsylla cheopis), but also through aerosols and airborne droplets for its pneumonic form. As a parasite of its host, the rat flea, which is also a parasite of rats, Y. pestis is a hyperparasite.

Y. pestis was discovered in 1894 by Alexandre Yersin, a Swiss/French physician and bacteriologist from the Pasteur Institute, during an epidemic of the plague in Hong Kong. Yersin was a member of the Pasteur school of thought. Kitasato Shibasaburō, a Japanese bacteriologist who practised Koch's methodology, was also engaged at the time in finding the causative agent of the plague. However, Yersin actually linked plague with a bacillus, initially named Pasteurella pestis; it was renamed Yersinia pestis in 1944.

The second plague pandemic was a major series of epidemics of plague that started with the Black Death, which reached medieval Europe in 1346 and killed up to half of the population of Eurasia in the next four years. It followed the first plague pandemic that began in the 6th century with the Plague of Justinian, which ended in the 8th century. Although the plague died out in most places after 1353, it became endemic and recurred regularly. A series of major epidemics occurred in the late 17th century, and the disease recurred in some places until the late 18th century or the early 19th century. After this, a new strain of the bacterium gave rise to the third plague pandemic, which started in Asia around the mid-19th century.

By the early 19th century, the threat of plague had diminished, though it was quickly replaced by the spread of another deadly infectious disease in the first cholera pandemic, beginning in 1817, the first of several cholera pandemics to sweep through Asia and Europe during the 19th and 20th centuries. One of the last epidemics to strike the Balkans during the second plague pandemic was Caragea's plague, between 1813 and 1814. The Swiss explorer Johann Ludwig Burckhardt witnessed the plague epidemics that ravaged Hejaz and Egypt between 1812 and 1816. He wrote: "In five or six days after my arrival [in Yanbu] the mortality increased; forty or fifty persons died in a day, which, in a population of five or six thousand, was a terrible mortality."Malta had its second most severe plague epidemic in the epidemic of 1813–1814, which killed around 4,500 people.

Pneumonic plague is a severe lung infection caused by the bacterium Yersinia pestis. Symptoms include fever, headache, shortness of breath, chest pain, coughing, and coughing up blood. They typically start about three to seven days after exposure. It is one of three forms of plague, the other two being septicemic plague and bubonic plague.

The pneumonic form may occur following an initial bubonic or septicemic plague infection. It may also result from breathing in airborne droplets from another person or animal infected with pneumonic plague. The difference between the forms of plague is the location of infection; in pneumonic plague the infection is in the lungs, in bubonic plague the lymph nodes, and in septicemic plague within the blood. Diagnosis is by testing the blood, sputum, or fluid from a lymph node.

The Flavian dynasty, lasting from 69 to 96 CE, was the second dynastic line of emperors to rule the Roman Empire following the Julio-Claudians, encompassing the reigns of Vespasian and his two sons, Titus and Domitian. The Flavians rose to power during the civil war of 69 CE, known as the Year of the Four Emperors; after Galba and Otho died in quick succession, Vitellius became emperor in mid 69. His claim to the throne was quickly challenged by legions stationed in the eastern provinces, who declared their commander Vespasian emperor in his place. The Second Battle of Bedriacum tilted the balance decisively in favor of the Flavian forces, who entered Rome on 20 December, and the following day, the Roman Senate officially declared Vespasian emperor, thus commencing the Flavian dynasty. Although the dynasty proved to be short-lived, several significant historic, economic and military events took place during their reign.

The reign of Titus was struck by multiple natural disasters, the most severe of which was the eruption of Mount Vesuvius in 79 CE, which saw the surrounding cities of Pompeii and Herculaneum be completely buried under ash and lava. One year later, Rome was struck by fire and a plague. On the military front, the Flavian dynasty witnessed the siege and destruction of Jerusalem by Titus in 70 CE, following the failed Jewish rebellion of 66. Substantial conquests were made in Great Britain under the command of Gnaeus Julius Agricola between 77 and 83 CE, while Domitian was unable to procure a decisive victory against King Decebalus in the war against the Dacians. In addition, the Empire strengthened its border defenses by expanding the fortifications along the Limes Germanicus.