Interstate 45 (I-45) is a major Interstate Highway located entirely within the U.S. state of Texas. While most primary Interstate routes which have numbers ending in "5" are cross-country north–south routes, I-45 is comparatively short, with the entire route located within Texas. Additionally, it has the shortest length of all the primary Interstates divisible by 5, and is the only Interstate Highway of such. It connects the cities of Dallas and Houston, continuing southeast from Houston to Galveston over the Galveston Causeway to the Gulf of Mexico.
I-45 replaced U.S. Highway 75 (US 75) over its entire length, although portions of US 75 remained parallel to I-45 until its elimination south of Downtown Dallas in 1987. At the south end of I-45, State Highway 87 (SH 87, formerly part of US 75) continues into downtown Galveston. The north end is at I-30 in Downtown Dallas, where US 75 used the Good-Latimer Expressway. A short continuation, known by traffic reporters as the I-45 overhead, signed as part of US 75 and also part of unsigned I-345, continues north to the merge with the current end of US 75. Traffic can use Spur 366 (better known locally as the Woodall Rodgers Freeway) to connect to I-35E at the north end of I-345.
