Greensboro (/ˈɡriːnzbəroʊ/ ; locally /ˈɡriːnzbʌrə/) is a city in Guilford County, North Carolina, United States, and its county seat. Its population was 299,035 in the 2020 census and estimated at 307,381 in 2024, making it the third-most populous city in North Carolina and the 69th-most populous city in the U.S. The Greensboro–High Point metropolitan area has an estimated 801,000 residents. It is the most populous city in North Carolina's Piedmont Triad region, home to about 1.7 million residents.
In 1808, Greensboro was planned around a central courthouse square to succeed Guilford Court House as the county seat. The county courts were thus placed closer to the county's geographical center, a location more easily reached at the time by the majority of the county's citizens, who traveled by horse or on foot. Three major Interstate Highways (Interstate 40, Interstate 85, and Interstate 73) in the Piedmont region of central North Carolina were built to intersect at this city.