Interstate 40 (I-40) is a major east–west transcontinental Interstate Highway in the southeastern and southwestern portions of the United States. At a length of 2,556.61 miles (4,114.46 km), it is the third-longest Interstate Highway in the country, after I-90 and I-80. From west to east, it passes through California, Arizona, New Mexico, Texas, Oklahoma, Arkansas, Tennessee, and North Carolina. Its western terminus is at I-15 in Barstow, California, while its eastern terminus is at a concurrency with U.S. Route 117 (US 117) and North Carolina Highway 132 (NC 132) in Wilmington, North Carolina. Major cities served by the Interstate include Flagstaff, Arizona; Albuquerque, New Mexico; Amarillo, Texas; Oklahoma City, Oklahoma; Fort Smith and Little Rock in Arkansas; Memphis, Nashville, and Knoxville in Tennessee; and Asheville, Winston-Salem, Greensboro, Durham, Raleigh, and Wilmington in North Carolina.
I-40 begins in the Mojave Desert in California, and then proceeds through the Colorado Plateau in Arizona and the southern tip of the Rocky Mountains in New Mexico. It then traverses the Great Plains through the Texas Panhandle and Oklahoma, and passes south of the Ozarks in Arkansas. The freeway crosses the Appalachian Mountains in Tennessee and North Carolina, before terminating in the Atlantic Coastal Plain near the Atlantic Ocean.