Domenico Ghirlandaio in the context of "Cristoforo Landino"

The ministry of Jesus, in the canonical gospels, begins with his baptism near the River Jordan by John the Baptist, and ends in Jerusalem in Judea, following the Last Supper with his disciples. The Gospel of Luke states that Jesus was "about 30 years of age" at the start of his ministry. A chronology of Jesus typically sets the date of the start of his ministry at around AD 27–29 and the end in the range AD 30–36.

Jesus' early Galilean ministry begins when after his baptism, he goes back to Galilee from his temptation in the Judaean Desert. In this early period, he preaches around Galilee and recruits his first disciples who begin to travel with him and eventually form the core of the early Church as it is believed that the apostles dispersed from Jerusalem to found the apostolic sees. The major Galilean ministry which begins in Matthew 8 includes the commissioning of the Twelve Apostles, and covers most of the ministry of Jesus in Galilee. The final Galilean ministry begins after the beheading of John the Baptist as Jesus prepares to go to Jerusalem.

God the Son (Greek: Θεὸς ὁ Υἱός, Latin: Deus Filius) or God the Word (Greek: Θεὸς ὁ Λόγος, Latin: Deus Verbum) is the second Person of the Trinity in Christian theology. According to mainstream Christian doctrine, God the Son, in the form of Jesus Christ, is the incarnation of the eternal, pre-existent divine Logos (Koine Greek for "word") through whom all things were created. Although the precise term "God the Son" does not appear in the Bible, it serves as a theological designation expressing the understanding of Jesus as a part of the Trinity, distinct yet united in essence with God the Father and God the Holy Spirit (the first and third Persons of the Trinity respectively).

The commissioning of the Twelve Apostles is an episode in the ministry of Jesus that appears in all three Synoptic Gospels: Matthew 10:1–4, Mark 3:13–19 and Luke 6:12–16. It relates the initial selection of the Twelve Apostles among the disciples of Jesus.

The Sistine Chapel (/ˈsɪstiːn/ SIST-een; Latin: Sacellum Sixtinum; Italian: Cappella Sistina [kapˈpɛlla siˈstiːna]) is a chapel in the Apostolic Palace, the pope's official residence in Vatican City. Originally known as the Cappella Magna ('Great Chapel'), it takes its name from Pope Sixtus IV, who had it built between 1473 and 1481. Since that time, it has served as a place of both religious and functionary papal activity. Today, it is the site of the papal conclave, the process by which a new pope is selected. The chapel's fame lies mainly in the frescoes that decorate its interior, most particularly the Sistine Chapel ceiling and The Last Judgment, both by Michelangelo.

During the reign of Sixtus IV, a team of Renaissance painters including Sandro Botticelli, Pietro Perugino, Pinturicchio, Domenico Ghirlandaio and Cosimo Rosselli, created a series of frescoes depicting the Life of Moses and the Life of Christ, offset by papal portraits above and trompe-l'œil drapery below. They were completed in 1482, and on 15 August 1483 Sixtus IV celebrated the first mass in the Sistine Chapel for the Feast of the Assumption, during which the chapel was consecrated and dedicated to the Virgin Mary.

The Vocation of the Apostles is a fresco by the Italian Renaissance painter Domenico Ghirlandaio, executed in 1481–1482 and located in the Sistine Chapel, Rome. It depicts the Gospel narrative of Jesus Christ calling Peter and Andrew to become his disciples.

Christ in Glory with Four Saints and a Donor is a c.1492 tempera on panel painting by Domenico Ghirlandaio and his studio.

It was commissioned by Giusto Bonvicini, abbot of the Camaldolese Santi Giusto e Clemente Abbey in Volterra - the two standing saints may be saints Giovanni Gualberto and Saint Romuald, linked to the Camaldolese Congregation. It was painted in Ghirlandaio's studio in Florence (only details and the original composition are thought to be by the master) and taken to Volterra, where it is now in the town's Pinacoteca e museo civico di Volterra.

Cosimo Rosselli (Italian: [ˈkɔːzimo rosˈsɛlli]; 1439–1507) was an Italian painter of the Quattrocento, active mainly in his birthplace of Florence, but also in Pisa earlier in his career and in 1481–82 in the Sistine Chapel in Rome, where he painted some of the large frescoes on the side walls.

Though generally regarded as a lesser talent in comparison to Sandro Botticelli, Pietro Perugino, and Domenico Ghirlandaio, who were all also active at the Sistine Chapel, Rosselli was still able to win large and important commission throughout his career, a testament to his high level of activity in his native Florence. Important local commissions include a fresco in the cloister of Santissima Annunziata, Florence and those in the Chapel of the Holy Blood in Sant'Ambrogio, Florence.

Davide Ghirlandaio (1452–1525), also known as David Ghirlandaio and as Davide Bigordi, was an Italian painter and mosaicist, active in his native Florence.

His brothers Benedetto Ghirlandaio (1458–1497) and Domenico Ghirlandaio (1449–1494) were both painters, as was his nephew Ridolfo Ghirlandaio (1483–1561).Davide was an assistant to, and then a partner of, his brother, the leading painter Domenico. After Domenico's death, Davide took over the studio and trained Domenico's son Ridolfo. He was active in the mosaic decoration of the Orvieto Cathedral.