Matthew 10 is the tenth chapter in the Gospel of Matthew in the New Testament section of the Christian Bible. This chapter opens with Jesus calling some of his disciples and sending them out to preach and heal. This chapter is also known as the Mission Discourse, the Apostolic Discourse, or the Little Commission, in contrast to the Great Commission at the end of the gospel (Matthew 28:18–20). The Apostles receiving the Little Commission are directed to enter only the towns of the "lost sheep of the house of Israel" in verse 6, but verse 18 mentions that they will also be a witness to "governors, kings and the Gentiles" while in those towns. In contrast, the Great Commission is specifically directed to all nations. This has led to debate as to whom the target audience of Jesus' original, pre-resurrection ministry was.
Matthew names the twelve apostles, or "twelve disciples", in verses 2 to 4, and gives them careful instruction as they travel around Israel. The remainder of the chapter consists almost entirely of sayings attributed to Jesus. Many of the sayings found in Matthew 10 are also found in Luke 10 and the Gospel of Thomas, which is not part of the accepted canon of the New Testament.
