Yellow fever in the context of "Flaviviridae"

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⭐ Core Definition: Yellow fever

Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains—particularly in the back—and headaches. Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever recurs, abdominal pain occurs and liver damage begins, causing yellow skin. If this occurs, the risk of bleeding and kidney problems is increased.

The disease is caused by the yellow fever virus and is spread by the bite of an infected mosquito. It infects humans, other primates, and several types of mosquitoes. In cities, it is spread primarily by Aedes aegypti, a type of mosquito found throughout the tropics and subtropics. The virus is an RNA virus of the genus Orthoflavivirus, with a full scientific name Orthoflavivirus flavi. The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood-sample testing with a polymerase chain reaction is required.

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👉 Yellow fever in the context of Flaviviridae

Flaviviridae, commonly flavivirus, flaviviral, and flaviviruses, is a family of enveloped positive-strand RNA viruses which mainly infect mammals and birds. They are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from the yellow fever virus; flavus is Latin for "yellow", and yellow fever in turn was named because of its propensity to cause jaundice in victims. There are 89 species in the family divided among four genera. Diseases associated with the group include: hepatitis (hepaciviruses), hemorrhagic syndromes, fatal mucosal disease (pestiviruses), hemorrhagic fever, encephalitis, and the birth defect microcephaly (flaviviruses).

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Yellow fever in the context of Hepatitis

Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pain, and diarrhea. Hepatitis is acute if it resolves within six months, and chronic if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer.

Hepatitis is most commonly caused by the virus hepatovirus A, B, C, D, and E. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever virus. Other common causes of hepatitis include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). Hepatitis A and E are mainly spread by contaminated food and water. Hepatitis B is mainly sexually transmitted, but may also be passed from mother to baby during pregnancy or childbirth and spread through infected blood. Hepatitis C is commonly spread through infected blood; for example, during needle sharing by intravenous drug users. Hepatitis D can only infect people already infected with hepatitis B.

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Yellow fever in the context of Ferdinand de Lesseps

Ferdinand Marie de Lesseps (French: [də lesɛps]; 19 November 1805 – 7 December 1894) was a French Orientalist diplomat and later developer of the Suez Canal, which in 1869, joined the Mediterranean and Red Seas, substantially reducing sailing distances and times between Europe and East Asia.

He attempted to repeat this success with an effort to build a Panama Canal at sea level during the 1880s, but the project was devastated by epidemics of malaria and yellow fever in the area, as well as by financial problems, and the planned Lesseps Panama Canal was never completed. Eventually, the project was bought out by the United States, which solved the medical problems and changed the design to a non-sea- level canal with locks. It was completed in 1914.

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Yellow fever in the context of Viral hepatitis

Viral hepatitis is liver inflammation due to a viral infection. It may present in acute form as a recent infection with relatively rapid onset, or in chronic form, typically progressing from a long-lasting asymptomatic condition up to a decompensated hepatic disease and hepatocellular carcinoma (HCC).

The most common causes of viral hepatitis are the five unrelated hepatotropic viruses hepatitis A, B, C, D, and E. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever. There also have been scores of recorded cases of viral hepatitis caused by herpes simplex virus.

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Yellow fever in the context of Pasteur Institute

The Pasteur Institute (French: Institut Pasteur, pronounced [ɛ̃stity pastœʁ]) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccines for anthrax and rabies. The institute was founded on 4 June 1887 and inaugurated on 14 November 1888.

For over a century, the Institut Pasteur has researched infectious diseases. This worldwide biomedical research organization based in Paris was the first to isolate HIV, the virus that causes AIDS, in 1983. It has also been responsible for discoveries that have enabled medical science to control diseases such as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, and plague.

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Yellow fever in the context of Benjamin Henry Latrobe

Benjamin Henry Boneval Latrobe (May 1, 1764 – September 3, 1820) was a British-American neoclassical architect who immigrated to the United States. He was one of the first formally trained, professional architects in the new United States, drawing on influences from his travels in Italy, as well as British and French Neoclassical architects such as Claude Nicolas Ledoux. In his thirties, he immigrated to the new United States and designed the United States Capitol, on "Capitol Hill" in Washington, D.C., as well as the Old Baltimore Cathedral or The Baltimore Basilica, (later renamed the Basilica of the National Shrine of the Assumption of the Blessed Virgin Mary). It is the first Cathedral constructed in the United States for any Christian denomination. Latrobe also designed the largest structure in America at the time, the "Merchants' Exchange" in Baltimore. With extensive balconied atriums through the wings and a large central rotunda under a low dome which dominated the city, it was completed in 1820 after five years of work and endured into the early twentieth century.

Latrobe immigrated to America from England in 1796, initially settling in Virginia where he worked on the Virginia State Penitentiary in Richmond. Latrobe then moved to Philadelphia where he established his practice. In 1803, he was hired as Surveyor of the Public Buildings of the United States, and spent much of the next fourteen years working on projects in the new national capital of Washington, D.C., where he served as the second Architect of the Capitol. He also was responsible for the design of the White House porticos. Latrobe spent the later years of his life in New Orleans, Louisiana working on a waterworks project, and died there in 1820 from yellow fever.

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Yellow fever in the context of Mosquito-borne disease

Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people contract mosquito-borne illnesses each year, resulting in nearly a million deaths.

Diseases transmitted by mosquitoes include malaria, dengue, West Nile virus, chikungunya, yellow fever, filariasis, tularemia, dirofilariasis, Japanese encephalitis, Saint Louis encephalitis, Western equine encephalitis, Eastern equine encephalitis, Venezuelan equine encephalitis, Ross River fever, Barmah Forest fever, La Crosse encephalitis, and Zika fever, as well as newly detected Keystone virus and Rift Valley fever. A preprint by Australian research group argues that Mycobacterium ulcerans, the causative pathogen of Buruli ulcer is also transmitted by mosquitoes.

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Yellow fever in the context of Simón Bolívar

Simón José Antonio de la Santísima Trinidad Bolívar y Palacios (24 July 1783 – 17 December 1830) was a Venezuelan statesman and military officer who led what are currently the countries of Colombia, Venezuela, Ecuador, Peru, Panama, and Bolivia to independence from the Spanish Empire. He is known colloquially as El Libertador, or the Liberator of America.

Simón Bolívar was born in Caracas in the Captaincy General of Venezuela into a wealthy family of American-born Spaniards (criollo) but lost both parents as a child. Bolívar was educated abroad and lived in Spain, as was common for men of upper-class families in his day. While living in Madrid from 1800 to 1802, he was introduced to Enlightenment philosophy and married María Teresa Rodríguez del Toro y Alaysa, who died in Venezuela from yellow fever in 1803. From 1803 to 1805, Bolívar embarked on a Grand Tour that ended in Rome, where he swore to end the Spanish rule in the Americas. In 1807, Bolívar returned to Venezuela and promoted Venezuelan independence to other wealthy creoles. When the Spanish authority in the Americas weakened due to Napoleon's Peninsular War, Bolívar became a zealous combatant and politician in the Spanish-American wars of independence.

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Yellow fever in the context of Aedes aegypti

Aedes aegypti (/ˈdz ˈɪpti/; US: /dz -, ˈdz -/; from Ancient Greek αηδής (aēdḗs) 'unpleasant' and Latin aegyptī 'Egyptian') – sometimes called the Egyptian mosquito, dengue mosquito, or yellow fever mosquito – is a mosquito that spreads diseases such as dengue fever, yellow fever, and chikungunya. The mosquito can be recognized by black and white markings on its legs and a marking in the form of a lyre on the upper surface of its thorax. The mosquito is native to north Africa, but is now a common invasive species that has spread to tropical, subtropical, and temperate regions throughout the world.

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