West Side Highway in the context of "One World Trade Center"

The Financial District of Lower Manhattan, also known as FiDi, is a neighborhood located on the southern tip of Manhattan in New York City. It is bounded by the West Side Highway on the west, Chambers Street and City Hall Park on the north, Brooklyn Bridge on the northeast, the East River to the southeast, and South Ferry and the Battery on the south.

The City of New York was created in the modern-day Financial District in 1624, and the neighborhood roughly overlaps with the boundaries of the New Amsterdam settlement in the late 17th century. The district comprises the offices and headquarters of many of the city's major financial institutions, including the New York Stock Exchange and the Federal Reserve Bank of New York. Anchored on Wall Street in the Financial District, New York City has been called both the leading financial center and the most economically powerful city of the world, and the New York Stock Exchange is the world's largest stock exchange by total market capitalization. Several other major exchanges have or had headquarters in the Financial District, including the New York Mercantile Exchange, NASDAQ, the New York Board of Trade, and the former American Stock Exchange.

Hudson Yards is a neighborhood on the West Side of Midtown Manhattan in New York City, bounded roughly by 30th Street in the south, 41st Street in the north, the West Side Highway in the west, and Eighth Avenue in the east. The area is the site of a large-scale redevelopment program that is being planned, funded, and constructed under a set of agreements among the State of New York, City of New York, and Metropolitan Transportation Authority (MTA), with the aim of expanding the Midtown Manhattan business district westward to the Hudson River. The program includes a major rezoning of the Far West Side, an extension of the New York City Subway's 7 and <7>​ trains to a new subway station at 34th Street and 11th Avenue, a renovation and expansion of the Javits Center, and a financing plan to fund the various components. The various components are being planned by the New York City Department of City Planning and New York City Economic Development Corporation.

The largest of the projects made possible by the rezoning is the 28-acre (11 ha) multiuse Hudson Yards real estate development by Related Companies and Oxford Properties, which is being built over the West Side Rail Yard. Construction began in 2012 with the groundbreaking for 10 Hudson Yards, and is projected to be completed by 2024. According to its master plan, created by Kohn Pedersen Fox Associates, the Hudson Yards development would include 16 skyscrapers to be constructed in two phases. Architects including Skidmore, Owings, and Merrill, Thomas Heatherwick, Roche-Dinkeloo, and Diller Scofidio + Renfro contributed designs for individual structures. Major office tenants include or will include Tapestry, Equinox Fitness, and BlackRock.

The West Side of Manhattan refers to the side of Manhattan Island that abuts the Hudson River and faces the U.S. state of New Jersey. The major neighborhoods on the West Side are (from north to south) Inwood, Hudson Heights, Washington Heights, West Harlem, Morningside Heights, Manhattan Valley, the Upper West Side, Hell's Kitchen, Chelsea, the West Village, SoHo, and Tribeca. The 8th Avenue and West Side subway lines connect all parts of the West Side.

The main north–south roads servicing the West Side are the Henry Hudson Parkway in the north and the West Side Highway in the south. The Hudson River Greenway separates these highways from the island's western shore.

34th Street is a major crosstown street in the New York City borough of Manhattan. It runs the width of Manhattan Island from the West Side Highway on the West Side to FDR Drive on the East Side. 34th Street is used as a crosstown artery between New Jersey to the west and Queens to the east, connecting the Lincoln Tunnel to New Jersey with the Queens–Midtown Tunnel to Long Island.

Several notable buildings are located directly along 34th Street, including the Empire State Building, Macy's Herald Square, and Javits Center. Other structures, such as Pennsylvania Station, are located within one block of 34th Street. The street is served by the crosstown M34/M34A bus routes and contains several subway stops.

59th Street is a crosstown street in the New York City borough of Manhattan, running from York Avenue and Sutton Place on the East Side of Manhattan to the West Side Highway on the West Side. The three-block portion between Columbus Circle and Grand Army Plaza is also known as Central Park South, since it forms the southern border of Central Park. There is a gap in the street between Ninth Avenue/Columbus Avenue and Columbus Circle, where the Deutsche Bank Center is located. While the Central Park South section is a bidirectional street, most of 59th Street carries one-way traffic.

59th Street forms the border between Midtown Manhattan and Upper Manhattan. North of 59th Street, the neighborhoods of the Upper West Side and Upper East Side continue on either side of Central Park. On the West Side, Manhattan's numbered avenues are renamed north of 59th Street: Eighth Avenue (at Columbus Circle) becomes Central Park West; Ninth Avenue is renamed Columbus Avenue; Tenth Avenue is renamed Amsterdam Avenue; and Eleventh Avenue becomes West End Avenue.

Houston Street (/ˈhaʊstən/ HOW-stən) is a major east–west thoroughfare in Lower Manhattan in New York City, New York. It runs the full width of the island of Manhattan, from FDR Drive along the East River in the east to the West Side Highway along the Hudson River in the west. The street is divided into west and east sections by Broadway.

Houston Street generally serves as the boundary between neighborhoods on the East Side of Manhattan—Alphabet City, the East Village, NoHo, Greenwich Village, and the West Village to the north; and the Lower East Side, most of the Bowery, Nolita, and SoHo to the south. The numeric street-naming grid in Manhattan, created as part of the Commissioners' Plan of 1811, begins immediately north of Houston Street with 1st Street at Avenue A.

Tribeca (/traɪˈbɛkə/ try-BEK-ə), originally written as TriBeCa, is a neighborhood in Lower Manhattan in New York City. Its name is a syllabic abbreviation of "Triangle Below Canal Street". The "triangle" (more accurately a quadrilateral) is bounded by Canal Street, West Street, Broadway, and Chambers Street. By the 2010s, a common marketing tactic was to extend Tribeca's southern boundary to either Vesey or Murray Streets to increase the appeal of property listings.

The neighborhood began as farmland, then was a residential neighborhood in the early 19th century, before becoming a mercantile area centered on produce, dry goods, and textiles, and then transitioning to artists and then actors, models, entrepreneurs, and other celebrities. The neighborhood is home to the Tribeca Festival, which was created in response to the September 11 attacks, to reinvigorate the neighborhood and downtown after the destruction caused by the terrorist attacks.