Valerian (emperor) in the context of "Gallienus"

The Battle of Manzikert or Malazgirt was fought between the Byzantine Empire and the Seljuk Empire on 26 August 1071 near Manzikert, Iberia (modern Malazgirt in Muş Province, Turkey). The decisive defeat of the Byzantine army and the capture of the emperor Romanos IV Diogenes played an important role in undermining Byzantine authority in Anatolia and Armenia, and allowed for the gradual Turkification of Anatolia. Many Turks, travelling westward during the 11th century, saw the victory at Manzikert as an entrance to Asia Minor.

The brunt of the battle was borne by the Byzantine army's professional soldiers from the eastern and western tagmata, as large numbers of mercenaries and Anatolian levies fled early and survived the battle. The fallout from Manzikert was disastrous for the Byzantines, resulting in civil conflicts and an economic crisis that severely weakened the Byzantine Empire's ability to defend its borders adequately. This led to the mass movement of Turks into central Anatolia – by 1080, an area of 78,000 square kilometres (30,000 sq mi) had been gained by the Seljuk Turks. It took three decades of internal strife before Alexius I (1081–1118) restored stability to Byzantium. Historian Thomas Asbridge says: "In 1071, the Seljuqs crushed an imperial army at the Battle of Manzikert (in eastern Asia Minor), and though historians no longer consider this to have been an utterly cataclysmic reversal for the Greeks, it still was a stinging setback." It was the only time a Byzantine emperor became the prisoner of a Muslim commander, and the first time since Valerian that a Roman emperor was captured alive by an enemy force.

Early Christians were heavily persecuted throughout the Roman Empire until the 3rd century. Although Christianity initially emerged as a small Jewish movement in 1st-century Judaea, it quickly branched off as a separate religion and began spreading across the various Roman territories at a pace that put it at odds with the well-established Roman imperial cult, to which it stood in opposition; Christians were vocal in their expressions of abhorrence towards the beliefs and practices of Roman paganism, such as deifying and making ritual sacrifices to the Roman emperor or partaking in other methods of idolatry. Consequently, the Roman state and other members of civic society routinely punished Christians for treason, various rumoured crimes, illegal assembly, and for introducing an alien cult that drove many Roman people to apostasy in favour of Jesus Christ. According to Tacitus, the first wave of organized persecution occurred under Nero (r. 54–68), who blamed Christians for the Great Fire of Rome in 64. A number of mostly localized persecutions occurred during the reign of Marcus Aurelius (r. 161–180). After a lull, persecution resumed under Decius (r. 249–251) and Trebonianus Gallus (r. 251–253). The Decian persecution was particularly extensive, as Decius strived to restore the Roman golden age in part by forcing pagan practices upon the Christian community. Another wave of persecution began under Valerian (r. 253–260), but ceased abruptly after he was captured and taken prisoner by the Sasanian Empire during the Battle of Edessa of the Roman–Persian Wars. Under his successor Gallienus (r. 253–268), whose reign was marred by rapidly escalating military conflicts of the Crisis of the Third Century, the first ever decree of tolerance was issued for Christian practices and places of worship, although it stopped short of recognizing Christianity as a religion with legal status.

Emperor Diocletian (r. 283–305) began the Diocletianic persecution, which was the final and the most severe wave of persecution of Christians by the Roman state. It was enforced until the accession of Galerius (r. 305–311), who issued the Edict of Serdica, and the death of Maximinus Daza (r. 310–313). After Constantine the Great (r. 306–337) defeated his rival Maxentius (r. 306–312) at the Battle of the Milvian Bridge in October 312, he and his co-emperor Licinius issued the Edict of Milan, which decriminalized Christianity and suppressed pagan populations throughout the Roman Empire. In 380, Theodosius I (r. 379–395) issued the Edict of Thessalonica, officially establishing Christianity as the Roman state religion. It was also during the reign of Theodosius I that pagan practices were overtly deemed punishable offenses, which laid the framework for early Byzantine anti-pagan policies.

The Battle of Edessa took place between the armies of the Roman Empire, under the command of Emperor Valerian, and the Sasanian Empire under Shapur I, in Edessa (now the Turkish city of Urfa) in 260. The Roman army was defeated and captured in its entirety by the Sasanian forces; for the first time, a Roman emperor was taken prisoner.

The Diocletianic or Great Persecution was the last and most severe persecution of Christians in the Roman Empire. In 303, the emperors Diocletian, Maximian, Galerius, and Constantius issued a series of edicts rescinding Christians' legal rights and demanding that they comply with traditional religious practices. Later edicts targeted the clergy and demanded universal sacrifice, ordering all inhabitants to sacrifice to the Roman gods (Jews were exempt). The persecution varied in intensity across the empire—weakest in Gaul and Britain, where only the first edict was applied, and strongest in the Eastern provinces. Persecutory laws were nullified by different emperors (Galerius with the Edict of Serdica in 311) at different times, but Constantine and Licinius' Edict of Milan in 313 has traditionally marked the end of the persecution.

Christians had been subject to intermittent local discrimination in the empire, but emperors prior to Diocletian were reluctant to issue general laws against the religious group. In the 250s, under the reigns of Decius and Valerian, Roman subjects including Christians were compelled to sacrifice to Roman gods or face imprisonment and execution, but there is no evidence that these edicts were specifically intended to attack Christianity. After Gallienus's accession in 260, these laws went into abeyance. Diocletian's assumption of power in 284 did not mark an immediate reversal of imperial inattention to Christianity, but it did herald a gradual shift in official attitudes toward religious minorities. In the first fifteen years of his rule, Diocletian purged the army of Christians, condemned Manicheans to death, and surrounded himself with public opponents of Christianity. Diocletian's preference for activist government, combined with his self-image as a restorer of past Roman glory, foreboded the most pervasive persecution in Roman history. In the winter of 302, Galerius urged Diocletian to begin a general persecution of the Christians. Diocletian was wary and asked the oracle at Didyma for guidance. The oracle's reply was read as an endorsement of Galerius's position, and a general persecution was called on 23 February 303.

Saint Lawrence or Laurence (Latin: Laurentius, lit. 'laurelled'; 31 December 225 – 10 August 258) was one of the seven deacons of the city of Rome under Pope Sixtus II who were martyred in the persecution of the Christians ordered by the Roman emperor Valerian in 258.

The Gallienus usurpers were the usurpers who claimed imperial power during the reign of Gallienus (253–268, the first part of which he shared with his father Valerian). The existence of usurpers during the Crisis of the Third Century was very common, and the high number of usurpers fought by Gallienus is due to his long rule; fifteen years being considered long by the standards of the 3rd century Roman Empire.