Early Christians were heavily persecuted throughout the Roman Empire until the 3rd century. Although Christianity initially emerged as a small Jewish movement in 1st-century Judaea, it quickly branched off as a separate religion and began spreading across the various Roman territories at a pace that put it at odds with the well-established Roman imperial cult, to which it stood in opposition; Christians were vocal in their expressions of abhorrence towards the beliefs and practices of Roman paganism, such as deifying and making ritual sacrifices to the Roman emperor or partaking in other methods of idolatry. Consequently, the Roman state and other members of civic society routinely punished Christians for treason, various rumoured crimes, illegal assembly, and for introducing an alien cult that drove many Roman people to apostasy in favour of Jesus Christ. According to Tacitus, the first wave of organized persecution occurred under Nero (r. 54–68), who blamed Christians for the Great Fire of Rome in 64. A number of mostly localized persecutions occurred during the reign of Marcus Aurelius (r. 161–180). After a lull, persecution resumed under Decius (r. 249–251) and Trebonianus Gallus (r. 251–253). The Decian persecution was particularly extensive, as Decius strived to restore the Roman golden age in part by forcing pagan practices upon the Christian community. Another wave of persecution began under Valerian (r. 253–260), but ceased abruptly after he was captured and taken prisoner by the Sasanian Empire during the Battle of Edessa of the Roman–Persian Wars. Under his successor Gallienus (r. 253–268), whose reign was marred by rapidly escalating military conflicts of the Crisis of the Third Century, the first ever decree of tolerance was issued for Christian practices and places of worship, although it stopped short of recognizing Christianity as a religion with legal status.
Emperor Diocletian (r. 283–305) began the Diocletianic persecution, which was the final and the most severe wave of persecution of Christians by the Roman state. It was enforced until the accession of Galerius (r. 305–311), who issued the Edict of Serdica, and the death of Maximinus Daza (r. 310–313). After Constantine the Great (r. 306–337) defeated his rival Maxentius (r. 306–312) at the Battle of the Milvian Bridge in October 312, he and his co-emperor Licinius issued the Edict of Milan, which decriminalized Christianity and suppressed pagan populations throughout the Roman Empire. In 380, Theodosius I (r. 379–395) issued the Edict of Thessalonica, officially establishing Christianity as the Roman state religion. It was also during the reign of Theodosius I that pagan practices were overtly deemed punishable offenses, which laid the framework for early Byzantine anti-pagan policies.
