Sack of Rome (1527) in the context of "High Renaissance"

The history of Rome includes the history of the city of Rome as well as the civilisation of ancient Rome. Roman history has been influential on the modern world, especially in the history of the Catholic Church, and Roman law has influenced many modern legal systems. Roman history can be divided into the following periods:

• Pre-historical and early Rome, covering Rome's earliest inhabitants and the legend of its founding by Romulus
• The period of Etruscan dominance and the regal period, in which, according to tradition, Romulus was the first of seven kings
• The Roman Republic, which commenced in 509 BC when kings were replaced with rule by elected magistrates. The period was marked by vast expansion of Roman territory. During the 5th century BC, Rome gained regional dominance in Latium. With the Punic Wars from 264 to 146 BC, ancient Rome gained dominance over the Western Mediterranean, displacing Carthage as the dominant regional power.
• The Roman Empire followed the Republic, which waned with the rise of Julius Caesar, and by all measures concluded after a period of civil war and the victory of Caesar's adopted son, Octavian, in 27 BC over Mark Antony.
• The Western Roman Empire collapsed in 476 after the city was conquered by the Ostrogothic Kingdom. Consequently, Rome's power declined, and it eventually became part of the Eastern Roman Empire, as the Duchy of Rome, from the 6th to 8th centuries. At this time, the city was reduced to a fraction of its former size, being sacked several times in the 5th to 6th centuries, even temporarily depopulated entirely.
• Medieval Rome is characterised by a break with Constantinople and the formation of the Papal States. The Papacy struggled to retain influence in the emerging Holy Roman Empire, and during the saeculum obscurum, the population of Rome fell to as low as 30,000 inhabitants. Following the East–West Schism and the limited success in the Investiture Controversy, the Papacy did gain considerable influence in the High Middle Ages, but with the Avignon Papacy and the Western Schism, the city of Rome was reduced to irrelevance, its population falling below 20,000. Rome's decline into complete irrelevance during the medieval period, with the associated lack of construction activity, assured the survival of very significant ancient Roman material remains in the centre of the city, some abandoned and others continuing in use.
• The Roman Renaissance occurred in the 15th century, when Rome replaced Florence as the centre of artistic and cultural influence. The Roman Renaissance was cut short abruptly with the devastation of the city in 1527, but the Papacy reasserted itself in the Counter-Reformation, and the city continued to flourish during the early modern period. Rome was annexed by Napoleon and was part of the First French Empire from 1809 to 1814.
• Modern history, the period from the 19th century to the present. Rome came under siege again after the Allied invasion of Italy and was bombed several times. It was declared an open city on 14 August 1943. Rome became the capital of the Italian Republic (established in 1946). With a population of 4.4 million (as of 2015; 2.9 million within city limits), it is the largest city in Italy. It is among the largest urban areas of the European Union and classified as a global city.

Girolamo Francesco Maria Mazzola (11 January 1503 – 24 August 1540), also known as Francesco Mazzola or, more commonly, as Parmigianino (UK: /ˌpɑːrmɪdʒæˈniːnoʊ/, US: /-dʒɑːˈ-/, Italian: [parmidʒaˈniːno]; "the little one from Parma"), was an Italian Mannerist painter and printmaker active in Florence, Rome, Bologna, and his native city of Parma. His work is characterized by a "refined sensuality" and often elongation of forms and includes Vision of Saint Jerome (1527) and the iconic if somewhat anomalous Madonna with the Long Neck (1534), and he remains the best known artist of the first generation whose whole careers fall into the Mannerist period.

His prodigious and individual talent has always been recognised, but his career was disrupted by war, especially the Sack of Rome in 1527, three years after he moved there, and then ended by his death at 37. He produced outstanding drawings, and was one of the first Italian painters to experiment with printmaking himself. While his portable works have always been keenly collected and are now in major museums in Italy and around the world, his two large projects in fresco are in a church in Parma and a palace in a small town nearby. This in conjunction with their lack of large main subjects has resulted in their being less well known than other works by similar artists. He painted a number of important portraits, leading a trend in Italy towards the three-quarters or full-length figure, previously mostly reserved for royalty.

The Landsknechte (singular: Landsknecht, pronounced [ˈlantsknɛçt]), also rendered as Landsknechts or Lansquenets, were German mercenaries used in pike and shot formations during the early modern period. Consisting predominantly of pikemen and supporting foot soldiers, their front line was formed by Doppelsöldner ("double-pay men") renowned for their use of Zweihänder and arquebus. They formed the bulk of the Holy Roman Empire's Imperial Army from the late 15th century to the early 17th century, fighting in the Habsburg-Valois wars, the Habsburg-Ottoman wars, and the European wars of religion.

Although prone to mutiny if unpaid and divided within their ranks between Catholics and Lutherans, the Landsknechte were well-armed and experienced warriors, recruitable in large numbers throughout Germany and Austria by the Holy Roman Emperor. This guaranteed both quantity and quality to the Imperial military for a century and a half. At their peak during the reign of Charles V of Habsburg, and under the leadership of notable captains such as Georg von Frundsberg and Nicholas of Salm, the Imperial Landsknechts obtained important successes such as the capture of the French King Francis I at the Battle of Pavia in 1525 and the resistance against the Ottoman Turks led by Suleiman the Magnificent at the Siege of Vienna in 1529, while also being responsible for the Sack of Rome in 1527.

Pope Paul III (Latin: Paulus III; Italian: Paolo III; born Alessandro Farnese; 29 February 1468 – 10 November 1549) was head of the Catholic Church and ruler of the Papal States from 13 October 1534 to his death, in November 1549.

Paul III came to the papal throne in the time following the sack of Rome in 1527, which was rife with uncertainties in the Catholic Church as the Protestant Reformation progressed. His pontificate initiated the Catholic Reformation with the Council of Trent in 1545, and witnessed wars of religion in which Emperor Charles V launched military campaigns against the Protestants in Germany. He recognized new Catholic religious orders and societies such as the Jesuits, the Barnabites, and the Congregation of the Oratory. His efforts were distracted by nepotism to advance the power and fortunes of his family, including his illegitimate son Pier Luigi Farnese.