Proton–proton chain reaction in the context of Coulomb repulsion

Deuterium fusion, also called deuterium burning, is a nuclear fusion reaction that occurs in stars and some substellar objects, in which a deuterium nucleus (deuteron) and a proton combine to form a helium-3 nucleus. It occurs as the second stage of the proton–proton chain reaction, in which a deuteron formed from two protons fuses with another proton, but can also proceed from primordial deuterium.

The proton–proton chain, also commonly referred to as the p–p chain, is one of two known sets of nuclear fusion reactions by which stars convert hydrogen to helium. It dominates in stars with masses less than or equal to that of the Sun, whereas the CNO cycle, the other known reaction, is suggested by theoretical models to dominate in stars with masses greater than about 1.3 solar masses.

In general, proton–proton fusion can occur only if the kinetic energy (temperature) of the protons is high enough to overcome their mutual electrostatic repulsion.

In astrophysics, the carbon–nitrogen–oxygen (CNO) cycle, sometimes called Bethe–Weizsäcker cycle, after Hans Albrecht Bethe and Carl Friedrich von Weizsäcker, is one of the two known sets of fusion reactions by which stars convert hydrogen to helium, the other being the proton–proton chain reaction (p–p cycle), which is more efficient at the Sun's core temperature. The CNO cycle is hypothesized to be dominant in stars that are more than 1.3 times as massive as the Sun.

Unlike the proton-proton reaction, which consumes all its constituents, the CNO cycle is a catalytic cycle. In the CNO cycle, four protons fuse, using isotopes of carbon, nitrogen, and oxygen as catalysts, each of which is consumed at one step of the CNO cycle, but re-generated in a later step. The end product is one alpha particle (a stable helium nucleus), two positrons, and two electron neutrinos.