NIN (cuneiform) in the context of "Cylinder seal"

Ninḫursaĝ (Sumerian: 𒀭𒎏𒄯𒊕 Ninḫarsang; NIN-ḪAR.SAG̃), sometimes transcribed Ninursag, Ninḫarsag, or Ninḫursaĝa, also known as Damgalnuna or Ninmah, was the ancient Sumerian mother goddess of the mountains, and one of the seven great deities of Sumer. She is known earliest as a nurturing or fertility goddess. She is the tutelary deity to several Sumerian leaders.

Her best-known myths are Enki and Ninhursag describing her dealings with Enki resulting from his sexual exploits, and Enki and Ninmah a creation myth wherein the two deities compete to create humans. She is referenced or makes brief appearances in others as well, most notably as the mother of Ninurta in the Anzû Epic.

Ninurta (Sumerian: 𒀭𒊩𒌆𒅁: NIN.URTA, possible meaning "Lord [of] Barley"), also known as Ninĝirsu (Sumerian: 𒀭𒊩𒌆𒄈𒋢: NIN.ĜIR₂.SU, meaning "Lord [of] Girsu"), is an ancient Mesopotamian god associated with farming, healing, hunting, law, scribes, and war who was first worshipped in early Sumer. In the earliest records, he is a god of agriculture and healing, who cures humans of sicknesses and releases them from the power of demons. In later times, as Mesopotamia grew more militarized, he became a warrior deity, though he retained many of his earlier agricultural attributes. He was regarded as the son of the chief god Enlil and his main cult center in Sumer was the Eshumesha temple in Nippur. Ninĝirsu was honored by King Gudea of Lagash (ruled 2144–2124 BC), who rebuilt Ninĝirsu's temple in Lagash. Later, Ninurta became beloved by the Assyrians as a formidable warrior. The Assyrian king Ashurnasirpal II (ruled 883–859 BC) built a massive temple for him at Kalhu, which became his most important cult center from then on.

In the epic poem Lugal-e, Ninurta slays the demon Asag using his talking mace Sharur and uses stones to build the Tigris and Euphrates rivers to make them useful for irrigation. In a poem sometimes referred to as the "Sumerian Georgica", Ninurta provides agricultural advice to farmers. In an Akkadian myth, he was the champion of the gods against the Anzû bird after it stole the Tablet of Destinies from his father Enlil and, in a myth that is alluded to in many works but never fully preserved, he killed a group of warriors known as the "Slain Heroes". His major symbols were a perched bird and a plow.

Puabi (Akkadian: 𒅤𒀜 pu3-AD fl. c. 2550 BC), also called Shubad or Shudi-Ad due to a misinterpretation by Sir Charles Woolley, was an important queen in the Sumerian city of Ur, during the First Dynasty of Ur. Commonly labeled as a "queen", her status is somewhat in dispute, although several cylinder seals in her tomb, labeled grave PG 800 at the Royal Cemetery at Ur, identify her by the title "nin" or "eresh", a Sumerian word denoting a queen or a priestess. Puabi's seal does not place her in relation to any king or husband, possibly indicating that she ruled in her own right. It has been suggested that she was the second wife of king Meskalamdug. Although little is known about Puabi's life, the discovery of Puabi's tomb and its death pit reveals important information as well as raises questions about Mesopotamian society and culture.

The meaning of Puabi's name is uncertain, though it could perhaps mean "word of my father" or "orchard of my father."

Ninlil (𒀭𒎏𒆤 NIN.LÍL; meaning uncertain) was a Mesopotamian goddess regarded as the wife of Enlil. She shared many of his functions, especially the responsibility for declaring destinies, and like him was regarded as a senior deity and head of the pantheon. She is also well attested as the mother of his children, such as the underworld god Nergal, the moon god Nanna or the warrior god Ninurta. She was chiefly worshiped in Nippur and nearby Tummal alongside Enlil, and multiple temples and shrines dedicated to her are attested in textual sources from these cities. In the first millennium BCE she was also introduced to Ḫursaĝkalamma near Kish, where she was worshiped alongside the goddess Bizilla, who was likely her sukkal (attendant deity).

At an early date Ninlil was identified with the goddess Sud from Shuruppak, like her associated with Enlil, and eventually fully absorbed her. In the myth Enlil and Sud, Ninlil is the name Sud received after marrying Enlil. Nisaba, the goddess of writing, and her husband Haya are described as her parents. While Ninlil's mother bears a different name, Nunbaršegunu, in the myth Enlil and Ninlil, the god list An = Anum states that it was an alternate name of Nisaba. Syncretism with Sud also resulted in Ninlil acquiring some of her unique characteristics, such as an association with healing goddesses and with Sudaĝ, a name of the wife of the sun god Shamash. References to these connections can be found in various Mesopotamian texts, such as a hymn referring to Ninlil as a healing goddess or a myth apparently confusing her with Sudaĝ in the role of mother of Ishum.