Linear particle accelerator in the context of "Radiation (medicine)"

⭐ In the context of radiation therapy, a linear particle accelerator is considered…

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⭐ Core Definition: Linear particle accelerator

A linear particle accelerator (often shortened to linac) is a type of particle accelerator that accelerates charged subatomic particles or ions to a high speed by subjecting them to a series of oscillating electric potentials along a linear beamline. The principles for such machines were proposed by Gustav Ising in 1924, while the first machine that worked was constructed by Rolf Widerøe in 1928 at the RWTH Aachen University.Linacs have many applications: they generate X-rays and high energy electrons for medicinal purposes in radiation therapy, serve as particle injectors for higher-energy accelerators, and are used directly to achieve the highest kinetic energy for light particles (electrons and positrons) for particle physics.

The design of a linac depends on the type of particle that is being accelerated: electrons, protons or ions. Linacs range in size from a cathode-ray tube (which is a type of linac) to the 3.2-kilometre-long (2.0 mi) linac at the SLAC National Accelerator Laboratory in Menlo Park, California.

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👉 Linear particle accelerator in the context of Radiation (medicine)

Radiation therapy or radiotherapy (RT, RTx, or XRT) is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. It is normally delivered by a linear particle accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body, and have not spread to other parts. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist and practicing radiographer are therapeutic radiographer.

Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue leading to cellular death. To spare normal tissues (such as skin or organs which radiation must pass through to treat the tumor), shaped radiation beams are aimed from several angles of exposure to intersect at the tumor, providing a much larger absorbed dose there than in the surrounding healthy tissue. Besides the tumor itself, the radiation fields may also include the draining lymph nodes if they are clinically or radiologically involved with the tumor, or if there is thought to be a risk of subclinical malignant spread. It is necessary to include a margin of normal tissue around the tumor to allow for uncertainties in daily set-up and internal tumor motion. These uncertainties can be caused by internal movement (for example, respiration and bladder filling) and movement of external skin marks relative to the tumor position.

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Linear particle accelerator in the context of Cavity magnetron

The cavity magnetron is a high-power vacuum tube used in early radar systems and subsequently in microwave ovens and in linear particle accelerators. A cavity magnetron generates microwaves using the interaction of a stream of electrons with a magnetic field, while moving past a series of cavity resonators, which are small, open cavities in a metal block. Electrons pass by the cavities and cause microwaves to oscillate within, similar to the functioning of a whistle producing a tone when excited by an air stream blown past its opening. The resonant frequency of the arrangement is determined by the cavities' physical dimensions. Unlike other vacuum tubes, such as a klystron or a traveling-wave tube (TWT), the magnetron cannot function as an amplifier for increasing the intensity of an applied microwave signal; the magnetron serves solely as an electronic oscillator generating a microwave signal from direct-current electricity supplied to the vacuum tube.

The use of magnetic fields as a means to control the flow of an electric current was spurred by the invention of the Audion by Lee de Forest in 1906. Albert Hull of General Electric Research Laboratory, USA, began development of magnetrons to avoid de Forest's patents, but these were never completely successful. Other experimenters picked up on Hull's work and a key advance, the use of two cathodes, was introduced by Habann in Germany in 1924. Further research was limited until Okabe's 1929 Japanese paper noting the production of centimeter-wavelength signals, which led to worldwide interest. The development of magnetrons with multiple cathodes was proposed by A. L. Samuel of Bell Telephone Laboratories in 1934, leading to designs by Postumus in 1934 and Hans Hollmann in 1935. Production was taken up by Philips, General Electric Company (GEC), Telefunken and others, limited to perhaps 10 W output. By this time the klystron was producing more power and the magnetron was not widely used, although a 300 W device was built by Aleksereff and Malearoff in the USSR in 1936 (published in 1940).

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Linear particle accelerator in the context of Particle accelerator

A particle accelerator is a machine that uses electromagnetic fields to propel charged particles to very high speeds and energies to contain them in well-defined beams. Small accelerators are used for fundamental research in particle physics. Accelerators are also used as synchrotron light sources for the study of condensed matter physics. Smaller particle accelerators are used in a wide variety of applications, including particle therapy for oncological purposes, radioisotope production for medical diagnostics, ion implanters for the manufacturing of semiconductors, and accelerator mass spectrometers for measurements of rare isotopes such as radiocarbon.

Large accelerators include the Relativistic Heavy Ion Collider at Brookhaven National Laboratory in New York, and the largest accelerator, the Large Hadron Collider near Geneva, Switzerland, operated by CERN. It is a collider accelerator, which can accelerate two beams of protons to an energy of 6.5 TeV and cause them to collide head-on, creating center-of-mass energies of 13 TeV. There are more than 30,000 accelerators in operation around the world.

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Linear particle accelerator in the context of Medical physics

Medical physics deals with the application of the concepts and methods of physics to the prevention, diagnosis and treatment of human diseases with a specific goal of improving human health and well-being. Since 2008, medical physics has been included as a health profession according to International Standard Classification of Occupation of the International Labour Organization.

Although medical physics may sometimes also be referred to as biomedical physics, medical biophysics, applied physics in medicine, physics applications in medical science, radiological physics or hospital radio-physics, a "medical physicist" is specifically a health professional with specialist education and training in the concepts and techniques of applying physics in medicine and competent to practice independently in one or more of the subfields of medical physics. Traditionally, medical physicists are found in the following healthcare specialties: radiation oncology (also known as radiotherapy or radiation therapy), diagnostic and interventional radiology (also known as medical imaging), nuclear medicine, and radiation protection. Medical physics of radiation therapy can involve work such as dosimetry, linac quality assurance, and brachytherapy. Medical physics of diagnostic and interventional radiology involves medical imaging techniques such as magnetic resonance imaging, ultrasound, computed tomography and x-ray. Nuclear medicine will include positron emission tomography, Single-photon emission computed tomography, and radionuclide therapy. However one can find Medical Physicists in many other areas such as physiological monitoring, audiology, neurology, neurophysiology, cardiology and others.

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