Antioch on the Maeander or Antiochia on the Maeander (Greek: Ἀντιόχεια τοῦ Μαιάνδρου; Latin: Antiochia ad Maeandrum), earlier Pythopolis, was a city of ancient Caria, in Anatolia, in modern-day Turkey. The city was situated between the Maeander and Orsinus rivers near their confluence. Though it was the site of a bridge over the Maeander, it had "little or no individual history". The scanty ruins are located on a hill (named, in Turkish, Yenişer) a few kilometers southeast of Kuyucak in Turkey's Aydın Province, near the modern city of Başaran, or the village of Aliağaçiftliği. The city already existed when Antiochus I enlarged and renamed it. It was home to the sophist Diotrephes.
The Venus de Milo is believed to have been sculpted by a citizen of Antioch named [...]andros (possibly Alexandros).