The Karluks (also Qarluqs, Qarluks, Karluqs, Old Turkic: 𐰴𐰺𐰞𐰸, Qarluq, Para-Mongol: Harluut, simplified Chinese: 葛逻禄; traditional Chinese: 葛邏祿 Géluólù ; customary phonetic: Gelu, Khololo, Khorlo, Persian: خَلُّخ, Khallokh, Arabic: قارلوق Qarluq) were a prominent nomadic Turkic tribal confederacy residing in the regions of Kara-Irtysh (Black Irtysh) and the Tarbagatai Mountains west of the Altay Mountains in Central Asia.
The majority of Uzbeks and Uyghurs indeed descend from Karluk tribes, and their languages are part of the Karluk subgroup, making them linguistically and historically distinct from other Turkic peoples like Kazakhs (Kipchak) or Turkmens (Oghuz).