Jennifer Doudna in the context of "CRISPR associated protein"

The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in chemistry, physics, literature, peace, and physiology or medicine. This award is administered by the Nobel Foundation and awarded by the Royal Swedish Academy of Sciences on proposal of the Nobel Committee for Chemistry, which consists of five members elected by the academy. The award is presented in Stockholm at an annual ceremony on December 10, the anniversary of Nobel's death.

The first Nobel Prize in Chemistry was awarded in 1901 to Jacobus Henricus van 't Hoff, of the Netherlands, "for his discovery of the laws of chemical dynamics and osmotic pressure in solutions". From 1901 to 2024, the award has been bestowed on a total of 195 individuals. The 2024 Nobel Prize in Chemistry was awarded to Demis Hassabis and John Jumper for protein structure prediction and to David Baker for Computational Protein Design. As of 2022, eight women had won the prize: Marie Curie (1911), her daughter Irène Joliot-Curie (1935), Dorothy Hodgkin (1964), Ada Yonath (2009), Frances Arnold (2018), Emmanuelle Charpentier and Jennifer Doudna (2020), and Carolyn R. Bertozzi (2022).

Emmanuelle Marie Charpentier (French pronunciation: [emanɥɛl maʁi ʃaʁpɑ̃tje]; born 11 December 1968) is a French professor and researcher in microbiology, genetics, and biochemistry. She has served as a director at the Max Planck Institute for Infection Biology in Berlin since 2015. Three years later, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing" (through CRISPR). This was the first science Nobel Prize ever won by two women only.

Walter Seff Isaacson (born May 20, 1952) is an American journalist who has written biographies of Henry Kissinger, Benjamin Franklin, Leonardo da Vinci, Albert Einstein, Steve Jobs, Jennifer Doudna, and Elon Musk. As of 2024, Isaacson is a professor at Tulane University and, since 2018, an interviewer for the PBS and CNN news show Amanpour & Company.

He has been the president and CEO of the Aspen Institute, a nonpartisan policy studies organization based in Washington, D.C., the chair and CEO of CNN, and the editor of Time.

CRISPR gene editing (/ˈkrɪspər/; pronounced like "crisper"; an abbreviation for "clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed or new ones added in vivo.

The technique is considered highly significant in biotechnology and medicine as it enables in vivo genome editing and is considered exceptionally precise, cost-effective, and efficient. It can be used in the creation of new medicines, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pests. It also offers potential in the treatment of inherited genetic diseases as well as diseases arising from somatic mutations, such as cancer. However, its use in human germline genetic modification is highly controversial. The development of this technique earned Jennifer Doudna and Emmanuelle Charpentier the Nobel Prize in Chemistry in 2020. The third researcher group that shared the Kavli Prize for the same discovery, led by Virginijus Šikšnys, was not awarded the Nobel Prize.