Inhalation (or inspiration) happens when air or other gases enter the lungs.
Inhalation (or inspiration) happens when air or other gases enter the lungs.
The lungs are the primary organs of the respiratory system in many animals, including humans. In mammals and most other tetrapods, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the atmosphere and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their musculoskeletal systems to support and foster breathing. In early tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the primary muscle that drives breathing is the diaphragm. The lungs also provide airflow that makes vocalisation including speech possible.
Humans have two lungs, a right lung and a left lung. They are situated within the thoracic cavity of the chest. The right lung is bigger than the left, and the left lung shares space in the chest with the heart. The lungs together weigh approximately 1.3 kilograms (2.9 lb), and the right is heavier. The lungs are part of the lower respiratory tract that begins at the trachea and branches into the bronchi and bronchioles, which receive air breathed in via the conducting zone. These divide until air reaches microscopic alveoli, where gas exchange takes place. Together, the lungs contain approximately 2,400 kilometers (1,500 mi) of airways and 300 to 500 million alveoli. Each lung is enclosed within a pleural sac of two pleurae which allows the inner and outer walls to slide over each other whilst breathing takes place, without much friction. The inner visceral pleura divides each lung as fissures into sections called lobes. The right lung has three lobes and the left has two. The lobes are further divided into bronchopulmonary segments and lobules. The lungs have a unique blood supply, receiving deoxygenated blood sent from the heart to receive oxygen (the pulmonary circulation) and a separate supply of oxygenated blood (the bronchial circulation).
Exhalation (or expiration) is the flow of the breath out of an organism. In animals, it is the movement of air from the lungs out of the airways, to the external environment during breathing.This happens due to elastic properties of the lungs, as well as the internal intercostal muscles which lower the rib cage and decrease thoracic volume. As the thoracic diaphragm relaxes during exhalation it causes the tissue it has depressed to rise superiorly and put pressure on the lungs to expel the air. During forced exhalation, as when blowing out a candle, expiratory muscles including the abdominal muscles and internal intercostal muscles generate abdominal and thoracic pressure, which forces air out of the lungs.
Exhaled air is 4% carbon dioxide, a waste product of cellular respiration during the production of energy, which is stored as ATP. Exhalation has a complementary relationship to inhalation which together make up the respiratory cycle of a breath.
Crying is the dropping of tears (or welling of tears in the eyes) in response to an emotional state or physical pain. Emotions that can lead to crying include sadness, anger, joy, and fear. Crying can also be caused by relief from a period of stress or anxiety, or as an empathetic response. The act of crying has been defined as "a complex secretomotor phenomenon characterized by the shedding of tears from the lacrimal apparatus, without any irritation of the ocular structures", instead, giving a relief which protects from conjunctivitis. A related medical term is lacrimation, which also refers to the non-emotional shedding of tears. Various forms of crying are known as sobbing, weeping, wailing, whimpering, bawling, and blubbering.
For crying to be described as sobbing, it usually has to be accompanied by a set of other symptoms, such as slow but erratic inhalation, occasional instances of breath holding, and muscular tremor.
Breathing (respiration or ventilation) is the rhythmic process of moving air into (inhalation) and out of (exhalation) the lungs to enable gas exchange with the internal environment, primarily to remove carbon dioxide and take in oxygen.
All aerobic organisms require oxygen for cellular respiration, which extracts energy from food and produces carbon dioxide as a waste product. External respiration (breathing) brings air to the alveoli where gases move by diffusion; the circulatory system then transports oxygen and carbon dioxide between the lungs and the tissues.
Apnea (also spelled apnoea in British English) is the temporary cessation of breathing, which may be voluntary or involuntary. During apnea, there is no movement of the muscles of inhalation, and the volume of the lungs initially remains unchanged. Depending on how blocked the airways are (patency), there may or may not be a flow of gas between the lungs and the environment. If there is sufficient flow, gas exchange within the lungs and cellular respiration would not be severely affected. Voluntarily doing this is called "holding one's breath".Apnea may first be diagnosed in childhood, and it is recommended to consult an ear-nose-throat specialist, allergist or sleep physician to discuss symptoms when noticed; malformation and/or malfunctioning of the upper airways may be observed by an orthodontist.
A cough is a sudden expulsion of air through the large breathing passages which can help clear them of fluids, irritants, foreign particles and microbes. As a protective reflex, coughing can be repetitive with the cough reflex following three phases: an inhalation, a forced exhalation against a closed glottis, and a violent release of air from the lungs following opening of the glottis, usually accompanied by a distinctive sound. Coughing into one's elbow or toward the ground—rather than forward at breathing height—can reduce the spread of infectious droplets in the air.
Frequent coughing usually indicates the presence of a disease. Many viruses and bacteria benefit, from an evolutionary perspective, by causing the host to cough, which helps to spread the disease to new hosts. Irregular coughing is usually caused by a respiratory tract infection but can also be triggered by choking, smoking, air pollution, asthma, gastroesophageal reflux disease, post-nasal drip, chronic bronchitis, lung tumors, heart failure and medications such as angiotensin-converting-enzyme inhibitors (ACE inhibitors) and beta blockers.
Absorption is the journey of a drug travelling from the site of administration to the site of action.
The drug travels by some route of administration (oral, topical-dermal, etc.) in a chosen dosage form (e.g., tablets, capsules, or in solution). Absorption by some other routes, such as intravenous therapy, intramuscular injection, enteral nutrition, is even more straightforward and there is less variability in absorption and bioavailability is often near 100%. Intravascular administration does not involve absorption, and there is no loss of drug. The fastest route of absorption is inhalation.