August Friedrich Leopold Weismann (German: [ˈvaɪsman]; 17 January 1834 – 5 November 1914) was a German evolutionary biologist. Fellow German Ernst Mayr ranked him as the second most notable evolutionary theorist of the 19th century, after Charles Darwin. Weismann became the Director of the Zoological Institute and the first Professor of Zoology at Freiburg.
His main contribution involved germ plasm theory, at one time also known as Weismannism, according to which inheritance (in a multicellular animal) only takes place by means of the germ cells—the gametes such as egg cells and sperm cells. Other cells of the body—somatic cells—do not function as agents of heredity. The effect is one-way: germ cells produce somatic cells and are not affected by anything the somatic cells learn or therefore any ability an individual acquires during its life. Genetic information cannot pass from soma to germ plasm and on to the next generation. Biologists refer to this concept as the Weismann barrier. This idea, if true, rules out the inheritance of acquired characteristics as proposed by Jean-Baptiste Lamarck. However, a careful reading of Weismann's work over the span of his entire career shows that he had more nuanced views, insisting, like Darwin, that a variable environment was necessary to cause variation in the hereditary material.