Galen in the context of "Logic"

Science in classical antiquity encompasses inquiries into the workings of the world or universe aimed at both practical goals (e.g., establishing a reliable calendar or determining how to cure a variety of illnesses) as well as more abstract investigations belonging to natural philosophy. Classical antiquity is traditionally defined as the period between the 8th century BC (beginning of Archaic Greece) and the 6th century AD (after which there was medieval science). It is typically limited geographically to the Greco-Roman West, Mediterranean basin, and Ancient Near East, thus excluding traditions of science in the ancient world in regions such as China and the Indian subcontinent.

Ideas regarding nature that were theorized during classical antiquity were not limited to science but included myths as well as religion. Those who are now considered as the first scientists may have thought of themselves as natural philosophers, as practitioners of a skilled profession (e.g., physicians), or as followers of a religious tradition (e.g., temple healers). Some of the more widely known figures active in this period include Hippocrates, Aristotle, Euclid, Archimedes, Hipparchus, Galen, and Ptolemy. Their contributions and commentaries spread throughout the Eastern, Islamic, and Latin worlds and contributed to the birth of modern science. Their works covered many different categories including mathematics, cosmology, medicine, and physics.

Scientific scholarship during the Byzantine Empire played an important role in the transmission of classical knowledge to the Islamic world and to Renaissance Italy, and also in the transmission of Islamic science to Renaissance Italy. Its rich historiographical tradition preserved ancient knowledge upon which splendid art, architecture, literature and technological achievements were built. Byzantines stood behind several technological advancements.

The history of science during the Age of Enlightenment traces developments in science and technology during the Age of Reason, when Enlightenment ideas and ideals were being disseminated across Europe and North America. Generally, the period spans from the final days of the 16th- and 17th-century Scientific Revolution until roughly the 19th century, after the French Revolution (1789) and the Napoleonic era (1799–1815). The scientific revolution saw the creation of the first scientific societies, the rise of Copernicanism, and the displacement of Aristotelian natural philosophy and Galen's ancient medical doctrine. By the 18th century, scientific authority began to displace religious authority, and the disciplines of alchemy and astrology lost scientific credibility.

While the Enlightenment cannot be pigeonholed into a specific doctrine or set of dogmas, science came to play a leading role in Enlightenment discourse and thought. Many Enlightenment writers and thinkers had backgrounds in the sciences and associated scientific advancement with the overthrow of religion and traditional authority in favour of the development of free speech and thought. Broadly speaking, Enlightenment science greatly valued empiricism and rational thought, and was embedded with the Enlightenment ideal of advancement and progress. As with most Enlightenment views, the benefits of science were not seen universally; Jean-Jacques Rousseau criticized the sciences for distancing man from nature and not operating to make people happier.

Aelius Nicon was a Greek architect and builder in 2nd century AD Pergamon. Nicon is known as the father of the ancient anatomist and philosopher, Galen.

Nicon was a mathematician, architect, astronomer, philosopher, and devotee of Greek literature. Nicon closely supervised Galen's education and tutored him at home, intending his son to study philosophy or politics. However, according to Galen, Nicon was visited in a dream by Asclepius, Greek god of healing, who told him to allow his son to study medicine. Galen soon began his studies at the major sanctuary of Asclepius located in Pergamon.

The history of biology traces the study of the living world from ancient to modern times. Although the concept of biology as a single coherent field arose in the 19th century, the biological sciences emerged from traditions of medicine and natural history reaching back to Ayurveda, ancient Egyptian medicine and the works of Aristotle, Theophrastus and Galen in the ancient Greco-Roman world. This ancient work was further developed in the Middle Ages by Muslim physicians and scholars such as Avicenna. During the European Renaissance and early modern period, biological thought was revolutionized in Europe by a renewed interest in empiricism and the discovery of many novel organisms. Prominent in this movement were Vesalius and Harvey, who used experimentation and careful observation in physiology, and naturalists such as Linnaeus and Buffon who began to classify the diversity of life and the fossil record, as well as the development and behavior of organisms. Antonie van Leeuwenhoek revealed by means of microscopy the previously unknown world of microorganisms, laying the groundwork for cell theory. The growing importance of natural theology, partly a response to the rise of mechanical philosophy, encouraged the growth of natural history (although it entrenched the argument from design).

Over the 18th and 19th centuries, biological sciences such as botany and zoology became increasingly professional scientific disciplines. Lavoisier and other physical scientists began to connect the animate and inanimate worlds through physics and chemistry. Explorer-naturalists such as Alexander von Humboldt investigated the interaction between organisms and their environment, and the ways this relationship depends on geography—laying the foundations for biogeography, ecology and ethology. Naturalists began to reject essentialism and consider the importance of extinction and the mutability of species. Cell theory provided a new perspective on the fundamental basis of life. These developments, as well as the results from embryology and paleontology, were synthesized in Charles Darwin's theory of evolution by natural selection. The end of the 19th century saw the fall of spontaneous generation and the rise of the germ theory of disease, though the mechanism of inheritance remained a mystery.

The history of anatomy spans from the earliest examinations of sacrificial victims to the advanced studies of the human body conducted by modern scientists. Written descriptions of human organs and parts can be traced back thousands of years to ancient Egyptian papyri, where attention to the body was necessitated by their highly elaborate burial practices.

Theoretical considerations of the structure and function of the human body did not develop until far later, in ancient Greece. Ancient Greek philosophers, like Alcmaeon and Empedocles, and ancient Greek doctors, like Hippocrates and his school, paid attention to the causes of life, disease, and different functions of the body. Aristotle advocated dissection of animals as part of his program for understanding the causes of biological forms. During the Hellenistic Age, dissection and vivisection of human beings took place for the first time in the work of Herophilos and Erasistratus. Anatomical knowledge in antiquity would reach its apex in the person of Galen, who made important discoveries through his medical practice and his dissections of monkeys, oxen, and other animals.

The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can cause disease. These small organisms, which are too small to be seen without magnification, invade animals, plants, and even bacteria. Their growth and reproduction within their hosts can cause disease. "Germ" refers not just to bacteria but to any type of microorganism, such as protists or fungi, or other pathogens, including parasites, viruses, prions, or viroids. Diseases caused by pathogens are called infectious diseases. Even when a pathogen is the principal cause of a disease, environmental and hereditary factors often influence the severity of the disease, and whether a potential host individual becomes infected when exposed to the pathogen. Pathogens are disease-causing agents that can pass from one individual to another, across multiple domains of life.

Basic forms of germ theory were proposed by Girolamo Fracastoro in 1546, and expanded upon by Marcus von Plenciz in 1762. However, such views were held in disdain in Europe, where Galen's miasma theory remained dominant among scientists and doctors.

Melancholia or melancholy (Ancient Greek: μελαγχολία, romanized: melancholía; from μέλαινα χολή, mélaina cholḗ, 'black bile') is a concept found throughout ancient, medieval, and premodern medicine in Europe that describes a condition characterized by markedly depressed mood, bodily complaints, and sometimes hallucinations and delusions. Besides a pathological condition, melancholy could also refer to a mood or temperament and at times it was even used as a description of the human condition in general.

Melancholy (or more precisely the 'black bile', from which melancholy derives its name) was regarded as one of the four temperaments matching the four humours. Until the 18th century, doctors and other scholars classified melancholic conditions as such by their perceived common cause – an excess of a notional fluid known as "black bile", which was commonly linked to the spleen. Hippocrates and other ancient physicians described melancholia as a distinct disease with mental and physical symptoms, including persistent fears and despondencies, poor appetite, abulia, sleeplessness, irritability, and agitation. Later, fixed delusions were added by Galen and other physicians to the list of symptoms. In the Middle Ages, the understanding of melancholia shifted to a religious perspective, with sadness seen as a vice and demonic possession, rather than somatic causes, as a potential cause of the disease.