Dengue in the context of "Morbilliform"

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⭐ Core Definition: Dengue

Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. Most cases of dengue fever are either asymptomatic or manifest mild symptoms. Symptoms typically begin 3 to 14 days after infection. They may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into severe dengue (previously known as dengue hemorrhagic fever or dengue shock syndrome) with bleeding, low levels of blood platelets, blood plasma leakage, and dangerously low blood pressure.

Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. The virus has four confirmed serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications, so-called antibody-dependent enhancement. The symptoms may resemble those of malaria, influenza, or Zika. Blood tests to confirm the diagnosis including detecting viral RNA, or specific antibodies.

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👉 Dengue in the context of Morbilliform

The term morbilliform refers to a rash that looks like measles. The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places. A morbilliform rash is a rose-red flat (macular) or slightly elevated (maculopapular) eruption, showing circular or elliptical lesions varying in diameter from 1 to 3 mm, with healthy-looking skin intervening.

Patients with measles will have the rash but there are other syndromes and infections that will display the same symptom such as patients with Kawasaki disease, meningococcal petechiae or Waterhouse-Friderichsen syndrome, Dengue, Roseola, congenital syphilis, rubella, Echovirus 9, drug hypersensitivity reactions (in particular with certain classes of antiretroviral drugs, such as abacavir and nevirapine, and also the antiepileptic drug phenytoin), or other conditions may also have a morbilliform rash. It is usually present in drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) following a prodrome of fever, malaise, throat pain with dysphagia, and itching. It has also been mentioned as a possible manifestation of onset or recovery from COVID-19.

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Dengue in the context of Mosquito-borne disease

Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people contract mosquito-borne illnesses each year, resulting in nearly a million deaths.

Diseases transmitted by mosquitoes include malaria, dengue, West Nile virus, chikungunya, yellow fever, filariasis, tularemia, dirofilariasis, Japanese encephalitis, Saint Louis encephalitis, Western equine encephalitis, Eastern equine encephalitis, Venezuelan equine encephalitis, Ross River fever, Barmah Forest fever, La Crosse encephalitis, and Zika fever, as well as newly detected Keystone virus and Rift Valley fever. A preprint by Australian research group argues that Mycobacterium ulcerans, the causative pathogen of Buruli ulcer is also transmitted by mosquitoes.

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Dengue in the context of Waterborne disease and climate change

Climate change is influencing the transmission and burden of many infectious diseases worldwide. Rising temperatures, shifting rainfall patterns, and more frequent extreme weather events affect how pathogens, vectors and disease hosts interact. These changes are altering the geographic ranges and seasonal activity of disease-carrying organisms such as mosquitoes and ticks, and influence the growth and survival of bacteria and other pathogens in food and water systems.

Infectious diseases that are sensitive to climate can be grouped into: vector-borne diseases (transmitted via mosquitos, ticks etc.), waterborne diseases (transmitted through viruses or bacteria in water), and food-borne diseases (spread through pathogens in food). In 2022 scientists stated a clear observation that "the occurrence of climate-related food-borne and waterborne diseases has increased."

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Dengue in the context of Tropical Medicine

Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions.

Physicians in this field diagnose and treat a variety of diseases and ailments. Most infections they deal with are endemic to the tropics. A few of the most well-known include malaria, HIV/AIDS, and tuberculosis. They must be knowledgeable in the 18 lesser known neglected tropical diseases, which include Chagas disease, rabies, and dengue. Poor living conditions in developing regions of tropical countries have led to a rising number of non-communicable diseases as well as the prevalence of neglected tropical diseases. These diseases include cancer and cardiovascular disease, which, in the past, have been more of a worry in developed countries. Physicians trained in tropical medicine must also be prepared to diagnose and treat these diseases.

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Dengue in the context of Tropical medicine

Tropical medicine is an interdisciplinary branch of medicine that deals with health issues that occur uniquely, are more widespread, or are more difficult to control in tropical and subtropical regions.

Physicians in this field diagnose and treat a variety of diseases and ailments. Most infections they deal with are endemic to the tropics. A few of the most well-known include malaria, HIV/AIDS, and tuberculosis. They must be knowledgeable in the 21 lesser known neglected tropical diseases, which include Chagas disease, rabies, dengue, lymphatic filariasis, onchocerciasis, schistosomiasis, and scabies. Poor living conditions in developing regions of tropical countries have led to a rising number of non-communicable diseases as well as the prevalence of neglected tropical diseases. These diseases include cancer and cardiovascular disease, which, in the past, have been more of a worry in developed countries. Physicians trained in tropical medicine must also be prepared to diagnose and treat these diseases.

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