Coenzyme Q10 in the context of Respiratory complex I

👉 Coenzyme Q10 in the context of Respiratory complex I

Respiratory complex I, EC 7.1.1.2 (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans. It catalyzes the transfer of electrons from NADH to coenzyme Q10 (CoQ10) and translocates protons across the inner mitochondrial membrane in eukaryotes or the plasma membrane of bacteria.

This enzyme is essential for the normal functioning of cells, and mutations in its subunits lead to a wide range of inherited neuromuscular and metabolic disorders. Defects in this enzyme are responsible for the development of several pathological processes such as ischemia/reperfusion damage (stroke and cardiac infarction), Parkinson's disease and others.

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Coenzyme Q10 in the context of Sporobolomyces

Sporobolomyces is a genus of fungi in the subdivision Pucciniomycotina. Species produce both yeast states and hyphal states. The latter form teliospores from which auricularioid (tubular and laterally septate) basidia emerge, bearing basidiospores. Yeast colonies are salmon-pink to red. Sporobolomyces species occur worldwide and have been isolated (as yeasts) from a wide variety of substrates. They produce ballistoconidia that are bilaterally symmetrical, they have Coenzyme Q₁₀ or Coenzyme Q₁₀(H₂) as their major ubiquinone, they lack xylose in whole-cell hydrolysates, and they cannot ferment sugars. One species, Sporobolomyces salmonicolor, is known to cause disease in humans.

View the full Wikipedia page for Sporobolomyces

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Coenzyme Q10 in the context of Respiratory complex I

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👉 Coenzyme Q10 in the context of Respiratory complex I

Coenzyme Q10 in the context of Sporobolomyces