Brugmansia in the context of "Tropane alkaloid"

A species that is extinct in the wild (EW) is one that has been categorized by the International Union for Conservation of Nature as only consisting of living members kept in captivity or as a naturalized population outside its historic range. Classification requires exhaustive surveys conducted within the species' known habitat with consideration given to seasonality, time of day, and life cycle. Once a species is classified as EW, the only way for it to be downgraded is through reintroduction.

Not all EW species are rare. An example is the Brugmansia genus, where all seven species are widely cultivated, but none are found in the wild.

Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives such as ketamine, due to their primary effect of causing delirium, as opposed to the more lucid and less disturbed states produced by other types of hallucinogens, where rational thought is better preserved (including the ability to distinguish hallucinations from reality). The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine.

Common examples of deliriants include plants of the genera Datura and Brugmansia, both containing scopolamine, as well as higher than recommended dosages of diphenhydramine (Benadryl). A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas, have been used by some indigenous cultures to reach delirious and altered states of consciousness for traditions or rituals, such as rites of passage, divination or communicating with the ancestors. Despite their long history of use, deliriants are the least-studied class of hallucinogens in terms of their behavioral and neurological effects.

Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.

In 2021, it was the 272nd most commonly prescribed medication in the United States, with more than 900,000 prescriptions.

Daturae is a tribe of flowering plants in the subfamily Solanoideae of the family Solanaceae. It comprises three genera: Datura, the Devil's trumpets, Brugmansia, the Angel's trumpets, and the monotypic Trompettia.

These plants are all genetically related. Phylogenetic research shows that Datura species evolved out of an ancestor shared with Nicotiana Tabacum. Whether or not Datura and Brugmansia species evolved out of each other is disputed.