Brain damage in the context of "Birth asphyxia"

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⭐ Core Definition: Brain damage

Brain injury, also known as brain damage or neurotrauma, is the destruction or degeneration of brain cells. It may result from external trauma, such as accidents or falls, or from internal factors, such as strokes, infections, or metabolic disorders.

Traumatic brain injury (TBI), the most common type of brain injury, is typically caused by external physical trauma to the head. Acquired brain injuries occur after birth, in contrast to congenital brain injuries that patients are born with.

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👉 Brain damage in the context of Birth asphyxia

Perinatal asphyxia (also known as neonatal asphyxia or birth asphyxia) is the medical condition resulting from deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain. It remains a serious condition which causes significant mortality and morbidity. It is also the inability to establish and sustain adequate or spontaneous respiration upon delivery of the newborn, an emergency condition that requires adequate and quick resuscitation measures. Perinatal asphyxia is also an oxygen deficit from the 28th week of gestation to the first seven days following delivery. It is also an insult to the fetus or newborn due to lack of oxygen or lack of perfusion to various organs and may be associated with a lack of ventilation. In accordance with WHO, perinatal asphyxia is characterised by: profound metabolic acidosis, with a pH less than 7.20 on umbilical cord arterial blood sample, persistence of an Apgar score of 3 at the 5th minute, clinical neurologic sequelae in the immediate neonatal period, or evidence of multiorgan system dysfunction in the immediate neonatal period. Hypoxic damage can occur to most of the infant's organs (heart, lungs, liver, gut, kidneys), but brain damage is of most concern and perhaps the least likely to quickly or completely heal. In more pronounced cases, an infant will survive, but with damage to the brain manifested as either mental, such as developmental delay or intellectual disability, or physical, such as spasticity.

It results most commonly from antepartum causes like a drop in maternal blood pressure or some other substantial interference with blood flow to the infant's brain during delivery. This can occur due to inadequate circulation or perfusion, impaired respiratory effort, or inadequate ventilation. Perinatal asphyxia happens in 2 to 10 per 1000 newborns that are born at term, and more for those that are born prematurely. WHO estimates that 4 million neonatal deaths occur yearly due to birth asphyxia, representing 38% of deaths of children under 5 years of age.

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Brain damage in the context of Amnesia

Amnesia is a deficit in memory caused by brain damage or brain diseases, but it can also be temporarily caused by the use of various sedative and hypnotic drugs. The memory can be either wholly or partially lost due to the extent of damage that is caused.

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Brain damage in the context of Neuroplasticity

Neuroplasticity, also known as neural plasticity or just plasticity, is the medium of neural networks in the brain to change through growth and reorganization. Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from its prior state. This process can occur in response to learning new skills, experiencing environmental changes, recovering from injuries, or adapting to sensory or cognitive deficits. Such adaptability highlights the dynamic and ever-evolving nature of the brain, even into adulthood. These changes range from individual neuron pathways making new connections, to systematic adjustments like cortical remapping or neural oscillation. Other forms of neuroplasticity include homologous area adaptation, cross modal reassignment, map expansion, and compensatory masquerade. Examples of neuroplasticity include circuit and network changes that result from learning a new ability, information acquisition, environmental influences, pregnancy, caloric intake, practice/training, and psychological stress.

Neuroplasticity was once thought by neuroscientists to manifest only during childhood, but research in the later half of the 20th century showed that many aspects of the brain exhibit plasticity through adulthood. The developing brain exhibits a higher degree of plasticity than the adult brain. Activity-dependent plasticity can have significant implications for healthy development, learning, memory, and recovery from brain damage.

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Brain damage in the context of Waterboarding

Waterboarding or controlled drowning is a form of torture in which water is poured over a cloth covering the face and breathing passages of an immobilized captive, causing the person to experience the sensation of drowning. In the most common method of waterboarding, the captive's face is covered with cloth or some other thin material and immobilized on their back at an incline of 10 to 20 degrees. Torturers pour water onto the face over the breathing passages, causing an almost immediate gag reflex and creating a drowning sensation for the captive. Normally, water is poured intermittently to prevent death; however, if the water is poured uninterruptedly it will lead to death by asphyxia. Waterboarding can cause extreme pain, damage to lungs, brain damage from oxygen deprivation, other physical injuries including broken bones due to struggling against restraints, and lasting psychological damage. Adverse physical effects can last for months, and psychological effects for years. The term "water board torture" appeared in press reports as early as 1976.

Waterboarding has been used in diverse places and at various points in history, including the Spanish and Flemish Inquisitions, by the United States military during the Philippine–American War, by Japanese and German officials during World War II, by the French in the Algerian War, by the U.S. during the Vietnam War and the war on terror, by the Pinochet regime in Chile, by the Khmer Rouge in Cambodia, by British security forces during the Troubles, and by South African police during the Apartheid era. Historically, waterboarding has been viewed as an especially severe form of torture.

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Brain damage in the context of Nonce word

In linguistics, a nonce word—also called an occasionalism—is any word (lexeme), or any sequence of sounds or letters, created for a single occasion or utterance but not otherwise understood or recognized as a word in a given language. Nonce words have a variety of functions and are most commonly used for humor, poetry, children's literature, linguistic experiments, psychological studies, and medical diagnoses, or they arise by accident.

Some nonce words have a meaning at their inception or gradually acquire a fixed meaning inferred from context and use, but if they eventually become an established part of the language (neologisms), they stop being nonce words. Other nonce words may be essentially meaningless and disposable (nonsense words), but they are useful for exactly that reason—the words wug and blicket for instance were invented by researchers to be used in child language testing. Nonsense words often share orthographic and phonetic similarity with (meaningful) words, as is the case with pseudowords, which make no sense but can still be pronounced in accordance with a language's phonotactic rules. Such invented words are used by psychology and linguistics researchers and educators as tools to assess a learner's phonetic decoding ability, and the ability to infer the (hypothetical) meaning of a nonsense word from context is used to test for brain damage. Proper names of real or fictional entities sometimes originate as nonce words.

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Brain damage in the context of Neurotoxicity

Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system. It occurs when exposure to a substance – specifically, a neurotoxin or neurotoxicant– alters the normal activity of the nervous system in such a way as to cause permanent or reversible damage to nervous tissue. This can eventually disrupt or even kill neurons, which are cells that transmit and process signals in the brain and other parts of the nervous system. Neurotoxicity can result from organ transplants, radiation treatment, certain drug therapies, recreational drug use, exposure to heavy metals, bites from certain species of venomous snakes, pesticides, certain industrial cleaning solvents, fuels and certain naturally occurring substances. Symptoms may appear immediately after exposure or be delayed. They may include limb weakness or numbness, loss of memory, vision, and/or intellect, uncontrollable obsessive and/or compulsive behaviors, delusions, headache, cognitive and behavioral problems and sexual dysfunction. Chronic mold exposure in homes can lead to neurotoxicity which may not appear for months to years of exposure. All symptoms listed above are consistent with mold mycotoxin accumulation.

The term neurotoxicity implies the involvement of a neurotoxin; however, the term neurotoxic may be used more loosely to describe states that are known to cause physical brain damage, but where no specific neurotoxin has been identified.

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Brain damage in the context of Anton's syndrome

Anton syndrome, also known as Anton–Babinski syndrome and visual anosognosia, is a rare symptom of brain damage occurring in the occipital lobe. Those who have it are cortically blind, but affirm, often quite adamantly and in the face of clear evidence of their blindness, that they are capable of seeing. Failing to accept being blind, people with Anton syndrome dismiss evidence of their condition and employ confabulation to fill in the missing sensory input. It is named after the neurologist Gabriel Anton. Only 28 cases have been published.

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Brain damage in the context of Suicide by gunshot

A suicide method is any means by which a person may choose to end their life. Suicide attempts do not always result in death, and a non-fatal suicide attempt can leave the person with serious physical injuries, long-term health problems, or brain damage.

Worldwide, three suicide methods predominate, with the pattern varying in different countries: these are hanging, pesticides, and firearms. Some suicides may be preventable by removing the means. Making common suicide methods less accessible leads to an overall reduction in the number of suicides.

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