Apostolic Chancery in the context of "Chancery hand"

Pope Alexander VI (Italian: Alessandro VI, Valencian: Alexandre VI, Spanish: Alejandro VI; born Roderic Llançol i de Borja; epithet: Valentinus ("The Valencian"); c. 1431 – 18 August 1503) was head of the Catholic Church and ruler of the Papal States from 11 August 1492 until his death in 1503.

Born into the prominent Borja family in Xàtiva in the Kingdom of Valencia under the Crown of Aragon (in present-day Spain), he was known as Roderic de Borja, and he is commonly referred to by the Italianized form as Rodrigo Borgia. He studied law at the University of Bologna. He was ordained deacon and made a cardinal in 1456 after the election of his uncle as Pope Callixtus III, and a year later he became vice-chancellor of the Catholic Church. He proceeded to serve in the Roman Curia under the next four popes, acquiring significant influence and wealth in the process. In 1492, Rodrigo was elected pope, taking the name Alexander VI.

The Palazzo della Cancelleria (Palace of the Chancellery, referring to the former Apostolic Chancery of the Pope) is a Renaissance palace in Rome, Italy, situated between the present Corso Vittorio Emanuele II and the Campo de' Fiori, in the rione of Parione. It was built 1489–1513 by Baccio Pontelli and Antonio da Sangallo the Elder as a palace for Raffaele Cardinal Riario, Camerlengo of the Holy Roman Church, and is regarded as the earliest Renaissance palace in Rome.

The Palazzo houses the institutions of justice of the Roman Curia, is an extraterritorial property of the Holy See, and is designated as a World Heritage Site.