Anastomosis in the context of "Microsurgery"

The Channeled Scablands are a relatively barren and soil-free region of interconnected relict and dry flood channels, coulees and cataracts and the typically flat-lying basalt flows that remain after cataclysmic floods. They are located in the southeastern part of Washington state. The Channeled Scablands were scoured by more than 40 cataclysmic floods during the Last Glacial Maximum and innumerable older cataclysmic floods over the last two million years. These floods were periodically unleashed whenever a large glacial lake broke through its ice dam and swept across eastern Washington and down the Columbia River Plateau during the Pleistocene epoch. The last of the cataclysmic floods occurred between 18,200 and 14,000 years ago. The floods eroded the area into the Palouse loess.

Geologist J Harlen Bretz defined "scablands" in a series of papers written in the 1920s as lowlands diversified by a multiplicity of irregular channels and rock basins eroded into basalt. Flood waters eroded the loess cover, creating large anastomizing channels that exposed bare basalt and creating butte-and-basin topography. The buttes range in height from 30 to 230 m (98 to 755 ft), while the rock basins range from 10 m (33 ft) in width up to the 11 km (7 mi) long and 30 m deep Rock Lake. Bretz further stated, "The channels run uphill and downhill, they unite and they divide, they head on the back-slopes and cut through the summit; they could not be more erratically and impossibly designed."

The parasexual cycle, a process restricted to fungi and single-celled organisms, is a nonsexual mechanism of parasexuality for transferring genetic material without meiosis or the development of sexual structures. It was first described by Italian geneticist Guido Pontecorvo in 1956 during studies on Aspergillus nidulans (also called Emericella nidulans when referring to its sexual form, or teleomorph). A parasexual cycle is initiated by the fusion of hyphae (anastomosis) during which nuclei and other cytoplasmic components occupy the same cell (heterokaryosis and plasmogamy). Fusion of the unlike nuclei in the cell of the heterokaryon results in formation of a diploid nucleus (karyogamy), which is believed to be unstable and can produce segregants by recombination involving mitotic crossing-over and haploidization. Mitotic crossing-over can lead to the exchange of genes on chromosomes; while haploidization probably involves mitotic nondisjunctions which randomly reassort the chromosomes and result in the production of aneuploid and haploid cells. Like a sexual cycle, parasexuality gives the species the opportunity to recombine the genome and produce new genotypes in their offspring. Unlike a sexual cycle, the process lacks coordination and is exclusively mitotic.

The parasexual cycle resembles sexual reproduction. In both cases, unlike hyphae (or modifications thereof) may fuse (plasmogamy) and their nuclei will occupy the same cell. The unlike nuclei fuse (karyogamy) to form a diploid (zygote) nucleus. In contrast to the sexual cycle, recombination in the parasexual cycle takes place during mitosis followed by haploidization (but without meiosis). The recombined haploid nuclei appear among vegetative cells, which differ genetically from those of the parent mycelium.