Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases.
Visceral fat, central abdominal fat, and waist circumference show a strong association with type 2 diabetes.
Pulcinella (Italian: [pultʃiˈnɛlla]; Neapolitan: Pulecenella) is a classical character that originated in commedia dell'arte of the 17th century and became a stock character in Neapolitan puppetry. Pulcinella's versatility in status and attitude have helped maintain the character's popularity in various forms since his introduction to commedia dell'arte by Silvio Fiorillo in 1620.
His visual appearance includes a humpback, a crooked nose, gangly legs, a potbelly, large cheeks, and a gigantic mouth. These traits were inherited from two stock characters of the Atellan Farce. He typically wears a pointed hat (conical hat). When depicted as a member of the upper class, Pulcinella is a cunning thief and schemer. When depicted as a member of the servant class, Pulcinella is a perverted bumpkin. In either case, he is a social climber, striving to rise above his station in life. He is an opportunist who always sides with the winner in any situation and who fears no consequences. His main motivations are self-interest and self-preservation, yet Pulcinella tends to rescue other characters from trouble. He is said to be every character's savior, despite acting as a rebel and a delinquent.
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals poorly. Women may have more hair and irregular menstruation or loss of menses, with the exact mechanisms of why still unknown. Occasionally there may be changes in mood, headaches, and a chronic feeling of tiredness.
Cushing's syndrome is caused by either excessive cortisol-like medication, such as prednisone, or a tumor that either produces or results in the production of excessive cortisol by the adrenal glands. Cases due to a pituitary adenoma are known as Cushing's disease, which is the second most common cause of Cushing's syndrome after medication. A number of other tumors, often referred to as ectopic due to their placement outside the pituitary, may also cause Cushing's. Some of these are associated with inherited disorders such as multiple endocrine neoplasia type 1 and Carney complex. Diagnosis requires a number of steps. The first step is to check the medications a person takes. The second step is to measure levels of cortisol in the urine, saliva or in the blood after taking dexamethasone. If this test is abnormal, the cortisol may be measured late at night. If the cortisol remains high, a blood test for ACTH may be done.
Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL).
Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities.