The Seille (French pronunciation: [sɛj]; German: Selle) is a river in north-eastern France. It is a right tributary of the Moselle. It is also known as the Seille lorraine or the Grande Seille ("large Seille"), to distinguish it from another Seille, a small tributary of the Saône.
It originates near Azoudange, in the department of Moselle. Leaving the Lindre lake, it skirts the town of Dieuze, and traverses Vic-sur-Seille and Nomeny, before flowing into the Moselle at Metz. It is 138 km long, and has a basin area of 1348 km. Most of its length is in the department of Moselle, except for the part between Aulnois-sur-Seille and Cheminot, which is in Meurthe-et-Moselle. The Seille also forms the border between Moselle and Meurthe-et-Moselle from Chambrey to Aulnois-sur-Seille.