The Tylihul Estuary also called Tylihulskyi lyman (Ukrainian: Тилігульський лиман) or simply Tiligul is a Ramsar-listed government protected estuary or liman of the Tylihul River. Located in Odesa Oblast in the south of Ukraine, the estuary includes an ornithological game reserve and the Tylihulskyi Regional Landscape Park situated on the East coast.
The name of the water body originates from the Turkish: Deli Göl, meaning "mad, rabid lake".
Odesa Oblast is the largest wine-growing region in Ukraine. As of 2018, wine production in Odesa Oblast covered 26.29 thousand hectares – 60.44% of the total area of vineyards in Ukraine.
The region is located in the favorable climate of the northwestern Black Sea coast, from the mouth of the Danube River to the Tylihul Estuary. According to 2015 data, grape production is carried out in 13 out of 26 districts (according to the previous administrative-territorial division of Ukraine). Agricultural enterprises produced 2,966,984.57 quintals of grapes in 2018.