Tiglath-Pileser III in the context of "Assyrian captivity"

The Neo-Assyrian Empire was the fourth and penultimate stage of ancient Assyrian history. Beginning with the accession of Adad-nirari II in 911 BC, the Neo-Assyrian Empire grew to dominate the ancient Near East and parts of South Caucasus, North Africa and Eastern Mediterranean throughout much of the 9th to 7th centuries BC, becoming the largest empire in history up to that point. Because of its geopolitical dominance and ideology based in world domination, the Neo-Assyrian Empire has been described as the first world empire in history. It influenced other empires of the ancient world culturally, administratively, and militarily, including the Neo-Babylonians, the Achaemenids, and the Seleucids. At its height, the empire was the strongest military power in the world and ruled over all of Mesopotamia, the Levant and Egypt, as well as parts of Anatolia, Arabia and modern-day Iran and Armenia.

The early Neo-Assyrian kings were chiefly concerned with restoring Assyrian control over much of northern Mesopotamia, eastern Anatolia and Levant, since significant portions of the preceding Middle Assyrian Empire (1365–1050 BC) had been lost during the late 11th century BC. Under Ashurnasirpal II (r. 883–859 BC), Assyria once more became the dominant power of the Near East, ruling the north undisputed. Ashurnasirpal's campaigns reached as far as the Mediterranean, and he oversaw the transfer of the imperial capital from the traditional city of Assur to the more centrally located Kalhu (later known as Calah in the Bible and Nimrud to the Medieval Arabs) The empire grew even more under Ashurnasirpal's successor Shalmaneser III (r. 859–824 BC), though it entered a period of stagnation after his death, referred to as the "age of the magnates". During this time, the chief wielders of political power were prominent generals and officials, and central control was unusually weak. This age came to an end with the rule of Tiglath-Pileser III (r. 745–727 BC), who re-asserted Assyrian royal power and more than doubled the size of the empire through wide-ranging conquests. His most notable conquests were Babylonia in the south and large parts of the Levant. Under the Sargonid dynasty, which ruled from 722 BC to the fall of the empire, Assyria reached its apex. Under Sennacherib (r. 705–681 BC), the capital was transferred to Nineveh, and under Esarhaddon (r. 681–669 BC) the empire reached its largest extent through the conquest of Egypt. Despite being at the peak of its power, the empire experienced a swift and violent fall in the late 7th century BC, destroyed by a Babylonian uprising and an invasion by the Medes. The causes behind how Assyria could be destroyed so quickly continue to be debated among scholars.

Sargon II (Neo-Assyrian Akkadian: 𒈗𒁺, romanized: Šarru-kīn, meaning "the faithful king" or "the legitimate king") was the king of the Neo-Assyrian Empire from 722 BC to his death in battle in 705. Probably the son of Tiglath-Pileser III (r. 745–727), Sargon is generally believed to have become king after overthrowing Shalmaneser V (r. 727–722), probably his brother. He is typically considered the founder of a new dynastic line, the Sargonid dynasty.

Modelling his reign on the legends of the ancient rulers Sargon of Akkad, from whom Sargon II likely took his regnal name, and Gilgamesh, Sargon aspired to conquer the known world, initiate a golden age and a new world order, and be remembered and revered by future generations. Over the course of his seventeen-year reign, Sargon substantially expanded Assyrian territory and enacted important political and military reforms. An accomplished warrior-king and military strategist, Sargon personally led his troops into battle. By the end of his reign, all of his major enemies and rivals had been either defeated or pacified. Among Sargon's greatest accomplishments were the stabilization of Assyrian control over the Levant, the weakening of the northern kingdom of Urartu, and the reconquest of Babylonia. From 717 to 707, Sargon constructed a new Assyrian capital named after himself, Dur-Sharrukin ('Fort Sargon'), which he made his official residence in 706.

Geshur (Biblical Hebrew: גְּשׁוּר, romanized: Gəšūr) was a territory in the ancient Levant mentioned in the early books of the Hebrew Bible and possibly in several other ancient sources, located in the region of the modern-day Golan Heights. Some scholars suggest it was established as an independent city-state during the early Iron Age from the middle of the tenth century BCE, maintaining its autonomy for about a century until it was annexed in the third quarter of the eighth century by Tiglath-Pileser III, the king of Assyria.

Ashur-nirari V (Neo-Assyrian cuneiform:  Aššur-nārāri, meaning "Ashur is my help") was the king of the Neo-Assyrian Empire from 755 BC to his death in 745 BC. Ashur-nirari was a son of Adad-nirari III (r. 811–783 BC) and succeeded his brother Ashur-dan III as king. He ruled during a period of Assyrian decline from which few sources survive. As such his reign, other than broad political developments, is poorly known.

At this time, the Assyrian officials were becoming increasingly powerful relative to the king, and Assyria's enemies were growing more dangerous. An unusually small share of Ashur-nirari's reign was devoted to campaigns against foreign enemies, perhaps suggesting domestic political instability within Assyria. In 746 or 745 BC, there are records of a revolt in Nimrud, the Assyrian capital. Ashur-nirari was succeeded by Tiglath-Pileser III, either his son or brother, but it is unclear in what manner. Though it is traditionally assumed that Tiglath-Pileser deposed Ashur-nirari, it is also possible that it was a smooth and legitimate succession, or that for a brief time they were co-rulers.