Lycia and Pamphylia (Latin: Lycia et Pamphylia; Koine Greek: Λυκία καὶ Παμφυλία, romanized: Lykía kaì Pamphylía) was the name of a province of the Roman Empire, located in southern Anatolia. It was created by the emperor Vespasian (r. 69–79), who merged Lycia and Pamphylia into a single administrative unit. In 43 AD, the emperor Claudius had annexed Lycia. Pamphylia had been a part of the province of Galatia.
The borders drawn by Vespasian ran west of the River Indus (which flowed from its upper valley in Caria) from the Pisidian plateau up to Lake Ascanius (Burdur Gölü), to the south of Apamea. In the north and east it formed a line which followed the shores of the lakes Limna (Hoyran Gölü) and Caralis (Beyşehir Gölü), turned south towards the Gulf of Adalla (mare Pamphylium) and followed the Taurus Mountains (Toros Dağları) for some ten miles towards east up to Isauria. It then followed Cilicia Trachea to reach the sea to the west of Iotape. The borders were drawn taking into account geographical and economic factors. The whole of the basins of the rivers Xanthus, Cestrus (Ak Su) and Eurymedon (Köprü Irmak) were included. The main cities were at the mouth of the latter two rivers. In Pisidia and in Pamphylia they were in part followed by the few roads into the interior of Anatolia. The most important one was the road from Attalea (Antalya) to Apamea. In Lycia the road from Patara towards Laodicea on the Lycus followed the coast. Important cities were Side, Ptolemais, Gagae and Myra on the coast, Seleucia, inland and Cremna, Colbhasa and Comama, on the Pisidian Plateau, where Augustus had founded Roman colonies (settlements). On the Milyas plateau there were Oenoanda, Tlos, Nisa, Podalia, Termessus, and Trebenna. Other important cities in Lycia include Pednelissus, Ariassus, and Sagalassus; along the Eurymedon, Aspendus and Perge, which had a sanctuary of Artemis. The most important city in the region was Patara, at the mouth of the Xanthus.