The Great North Road is a major route in Zambia, running north from Lusaka through Kabwe, Kapiri Mposhi (the road continues by way of a right turn just north of Kapiri Mposhi), Serenje, Mpika, Isoka and Nakonde to the border with Tanzania. The entire route is designated as the T2 road on Zambia's road network. It forms the Zambian section of the Tanzam Highway.
Originally, the Great North Road continued as the route from Mpika northwards, through Kasama, to Mbala. Then, when the route from Mpika to Nakonde and Tanzania (the Tanzam Highway) was upgraded in the 1960s and provided a good route through to Dar es Salaam and Arusha, this section became known as the Great North Road rather than the Mpika-Mbala section which might be referred to as the Old Great North Road.