Murakami Yoshikiyo (村上 義清, 1501–1573) was a Japanese samurai from the Murakami clan and retainer of the Uesugi clan during the Sengoku period of the 16th century. Yoshikiyo followed in fighting against both Takeda Nobutora and his son Takeda Shingen. Yoshikiyo was also a very close ally under Uesugi Kenshin and one of Shingen's bitterest opponents for his high kill-counts in their conflicts.
Before Murakami came into conflict with Takeda, they had good diplomatic relations as Yoshikiyo had sent back Oi Sadataka, a common enemy of both Murakami and Takeda when he was captured in Murakami's domain back to Takeda's base city of Kōfu as a prisoner for execution.