The Srem District (Serbian: Сремски округ, romanized: Sremski okrug, pronounced [srɛ̂ːmskiː ôkruːɡ]) is one of administrative districts of Serbia. It lies in the geographical regions of Syrmia and Mačva. According to the 2022 census, the Srem District has a population of 282,547 inhabitants. The administrative center is the city of Sremska Mitrovica.