Bautzen (German pronunciation: [ˈbaʊtsn̩] ) or Budyšin (Upper Sorbian pronunciation: [ˈbudɨʃin] ), until 1868 Budissin in German, is a town in eastern Saxony, Germany, and the administrative centre of the district of Bautzen. It is located on the Spree river, is the eighth most populous town in Saxony, and is the seat of Saxony's largest district. Bautzen lies in the bilingual Sorbian settlement area (Serbski sydlenski rum) of Lusatia, and is Lusatia's third-largest town after Cottbus and Görlitz, as well as the second-largest town in Upper Lusatia.
The town lies in the hilly Upper Lusatian Gefilde (Hornjołužiske hona), a part of the northwesternmost foothills of the Sudetes, just north of the Lusatian Highlands. Bautzen is the first larger town on the Spree River (Spree→ Havel→ Elbe→ North Sea), and the Bautzen Reservoir (Budyska rěčna zawěra) lies in the north of the town. In 2021, Bautzen had a population of around 38,000.