Polydora (/ˌpɒlɪˈdɔːrə/; Ancient Greek: Πολυδώρα, romanized: Poludṓra in Attic and Πολυδώρη in Ionic, means 'many-gifts' or 'the shapely') was the name of several characters in Greek mythology:
- Polydora, the 'handsome' Oceanid, one of the 3,000 water-nymph daughters of the Titans Oceanus and his sister-spouse Tethys.
- Polydora, a nymph and one of the 50 Danaïdes, daughter of King Danaus. She was the mother of King Dryops of Oeta, by the river-gods Spercheus or Peneus.
- Polydora, wife of Aphareus of Messenia and thus, the possible mother of his children, Idas, Lynceus and Peisus. In some accounts, the consort of Aphareus was called Arene or Laocoosa.
- Polydora, daughter of Peleus and Antigone, daughter of King Eurytion of Phthia. She married Borus, son of Perieres, who wooed her with large dowry, but regardless of this, Polydora became the mother of Menesthius by Spercheios.
- Polydora, daughter of Perieres and wife of Peleus. In some accounts, she became the mother of Menesthius by Spercheus.
- Polydora, daughter of Meleager and Cleopatra. She was married to Protesilaus, and after his death she was so affected by grief that she took her own life.
- Polydora, one of the Amazons.