Human presence in space (also anthropogenic presence in space or humanity in space) is the direct and mediated presence or telepresence of humans in outer space, and in an extended sense across space including astronomical bodies. Human presence in space, particularly through mediation, can take many physical forms from space debris, uncrewed spacecraft, artificial satellites, space observatories, crewed spacecraft, art in space, to human outposts in outer space such as space stations.
While human presence in space, particularly its continuation and permanence can be a goal in itself, human presence can have a range of purposes and modes from space exploration, commercial use of space to extraterrestrial settlement or even space colonization and militarisation of space. Human presence in space is realized and sustained through the advancement and application of space sciences, particularly astronautics in the form of spaceflight and space infrastructure.