Berbice (/bɜːrˈbiːs/) is a region along the Berbice River in Guyana, which was between 1627 and 1792 a colony of the Dutch West India Company and between 1792 and 1815 a colony of the Dutch state. After having been ceded to the United Kingdom of Great Britain and Ireland in the latter year, it was merged with Demerara-Essequibo to form the colony of British Guiana in 1831. It became a county of British Guiana in 1838 till 1958. In 1966, British Guiana gained independence as Guyana and in 1970 it became a republic as the Co-operative Republic of Guyana.
After being a hereditary fief in the possession of the Van Peere family, the colony was governed by the Society of Berbice in the second half of the colonial period, akin to the neighbouring colony of Suriname, which was governed by the Society of Suriname. The capital of Berbice was at Fort Nassau until 1790. In that year, the town of New Amsterdam, which grew around Fort Sint Andries, was made the new capital of the colony.