Simplon Tunnel in the context of "Simplon Railway"

Milano Centrale (Italian: Stazione di Milano Centrale) is the main railway station of the city of Milan, Northern Italy, and is the second busiest railway station in Italy for passenger flow (after Roma Termini) and the largest railway station in Europe by volume.

The station is a terminus and located at the northern end of central Milan. It was officially inaugurated in 1931 to replace the old central station (built 1864), which was a transit station that could not handle the increased traffic caused by the opening of the Simplon Tunnel in 1906 due to the old station's limited number of tracks and space.

The Lepontine Alps (German: Lepontinische Alpen, French: Alpes lépontines, Italian: Alpi Lepontine) are a mountain range in the north-western part of the Alps. They are located in Switzerland (Valais, Ticino, Uri and Graubünden) and Italy (Piedmont and Lombardy).

The Simplon rail tunnel (from Brig to Domodossola), the Gotthard rail (from Erstfeld to Bodio) and Gotthard road tunnels (from Andermatt to Airolo) and the San Bernardino road tunnel are important transport arteries.

The Orient Express was a long-distance passenger luxury train service created in 1883 by the Belgian company Compagnie Internationale des Wagons-Lits (CIWL) that operated until 2009. The train traveled the length of continental Europe, with terminal stations in Paris in the northwest and Istanbul in the southeast, and branches extending service to Athens, Brussels, and London.

The Orient Express embarked on its initial journey on 5 June 1883, from Paris to Vienna, eventually extending to Istanbul, thus connecting the western and eastern extremities of Europe. The route saw alterations and expansions, including the introduction of the Simplon Orient Express following the opening of the Simplon Tunnel in 1919, enhancing the service's allure and importance. Several routes concurrently used the Orient Express name, or variations. Although the original Orient Express was simply a normal international railway service, the name became synonymous with intrigue and luxury rail travel. The city names most prominently served and associated with the Orient Express are Paris and Istanbul, the original termini of the timetabled service. The rolling stock of the Orient Express changed many times.