The Portuguese–Safavid wars or Persian-Portuguese wars (Persian: جنگهای ایران و پرتغال) were a series of wars between the Portuguese Empire and Safavid Iran from 1507 to 1728. The Portuguese were also supported by Kingdom of Hormuz, its vassal, and Safavids had the help of the Kingdom of England on the other side.
During this era, Portugal established its rule for about more than a century in Hormuz and more than 80 years in Bahrain, capturing some other islands and ports such as Qeshm and Bandar Abbas. The conflict came to an end when the Persian shah Abbas I (r. 1588–1629), conquered Portuguese Bahrain, forcing them to war in the Persian Gulf.