Central Maluku Regency (Indonesian: Kabupaten Maluku Tengah) is a regency of Maluku Province of Indonesia. The Regency covers an area of 11,595.57 km, and had a population of 361,698 at the 2010 Census, and 423,094 at the 2020 Census. The official estimate as at mid 2024 was 432,361. The principal towns are Masohi (the administrative capital) and Amahai, both on Seram Island. The regency (kebupaten) is composed of the central part of the island of Seram, the Banda Islands, and the Lease Islands (Saparua, Haruku, and Nusa Laut), together with those parts of Ambon Island which are outside the City of Ambon.
This regency is the largest in area among Malukan regencies.