The region of Palestine is part of the wider region of the Levant, which represents the land bridge between Africa and Eurasia. The areas of the Levant traditionally serve as the "crossroads of Western Asia, the Eastern Mediterranean, and Northeast Africa", and in tectonic terms are located in the "northwest of the Arabian Plate". Palestine itself was among the earliest regions to see human habitation, agricultural communities and civilization. Because of its location, it has historically been seen as a crossroads for religion, culture, commerce, and politics. In the Bronze Age, the Canaanites established city-states influenced by surrounding civilizations, among them Egypt, which ruled the area in the Late Bronze Age. During the Iron Age, two related Israelite kingdoms, Israel and Judah, controlled much of Palestine, while the Philistines occupied its southern coast. The Assyrians conquered the region in the 8th century BCE, then the Babylonians c. 601 BCE, followed by the Persian Achaemenid Empire that conquered the Babylonian Empire in 539 BCE. Alexander the Great conquered the Persian Empire in the late 330s BCE, beginning Hellenization.
In the late 2nd-century BCE Maccabean Revolt, the Jewish Hasmonean Kingdom conquered most of Palestine; the kingdom subsequently became a vassal of Rome, which annexed it in 63 BCE. Roman Judea was troubled by Jewish revolts in 66 CE, so Rome destroyed Jerusalem and the Second Jewish Temple in 70 CE. In the 4th century, as the Roman Empire adopted Christianity, Palestine became a center for the religion, attracting pilgrims, monks and scholars. Following Muslim conquest of the Levant in 636–641, ruling dynasties succeeded each other: the Rashiduns; Umayyads; Abbasids; the semi-independent Tulunids and Ikhshidids; Fatimids; and the Seljuks. In 1099, the First Crusade resulted in Crusaders establishing of the Kingdom of Jerusalem, which was reconquered by the Ayyubid Sultanate in 1187. Following the invasion of the Mongol Empire in the late 1250s, the Egyptian Mamluks reunified Palestine under its control, before the region was conquered by the Ottoman Empire in 1516, being ruled as Ottoman Syria until the 20th century largely without dispute.
