Self-replication is any behavior of a dynamical system that yields construction of an identical or similar copy of itself. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction. Biological viruses can replicate, but only by commandeering the reproductive machinery of cells through a process of infection. Harmful prion proteins can replicate by converting normal proteins into rogue forms. Computer viruses reproduce using the hardware and software already present on computers. Self-replication in robotics has been an area of research and a subject of interest in science fiction. Any self-replicating mechanism which does not make a perfect copy (mutation) will experience genetic variation and will create variants of itself. These variants will be subject to natural selection, since some will be better at surviving in their current environment than others and will out-breed them.
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👉 Self-replication in the context of Cell (biology)
The cell is the basic structural and functional unit of all forms of life or organisms. The term comes from the Latin word cellula meaning 'small room'. A biological cell basically consists of a semipermeable cell membrane enclosing cytoplasm that contains genetic material. Most cells are only visible under a microscope. Except for highly-differentiated cell types (examples include red blood cells and gametes) most cells are capable of replication, and protein synthesis. Some types of cell are motile. Cells emerged on Earth about four billion years ago.
All organisms are grouped into prokaryotes, and eukaryotes. Prokaryotes are single-celled, and include archaea, and bacteria. Eukaryotes can be single-celled or multicellular, and include protists, plants, animals, most types of fungi, and some species of algae. All multicellular organisms are made up of many different types of cell. The diploid cells that make up the body of a plant or animal are known as somatic cells, and in animals excludes the haploid gametes.
Self-replication in the context of Cradle of life
Abiogenesis or the origin of life (sometimes called biopoesis) is the natural process by which life arises from non-living matter, such as simple organic compounds. The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was not a single event, but a process of increasing complexity involving the formation of a habitable planet, the prebiotic synthesis of organic molecules, molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. The transition from non-life to life has not been observed experimentally, but many proposals have been made for different stages of the process.
The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It uses tools from biology and chemistry, attempting a synthesis of many sciences. Life functions through the chemistry of carbon and water, and builds on four chemical families: lipids for cell membranes, carbohydrates such as sugars, amino acids for protein metabolism, and the nucleic acids DNA and RNA for heredity. A theory of abiogenesis must explain the origins and interactions of these classes of molecules.
Self-replication in the context of John von Neumann
John von Neumann (/vɒn ˈnɔɪmən/ von NOY-mən; Hungarian: Neumann János Lajos [ˈnɒjmɒn ˈjaːnoʃ ˈlɒjoʃ]; December 28, 1903 – February 8, 1957) was a Hungarian and American mathematician, physicist, computer scientist and engineer. Von Neumann had perhaps the widest coverage of any mathematician of his time, integrating pure and applied sciences and making major contributions to many fields, including mathematics, physics, economics, computing, and statistics. He was a pioneer in building the mathematical framework of quantum physics, in the development of functional analysis, and in game theory, introducing or codifying concepts including cellular automata, the universal constructor and the digital computer. His analysis of the structure of self-replication preceded the discovery of the structure of DNA.
During World War II, von Neumann worked on the Manhattan Project. He developed the mathematical models behind the explosive lenses used in the implosion-type nuclear weapon. Before and after the war, he consulted for many organizations including the Office of Scientific Research and Development, the Army's Ballistic Research Laboratory, the Armed Forces Special Weapons Project and the Oak Ridge National Laboratory. At the peak of his influence in the 1950s, he chaired a number of Defense Department committees including the Strategic Missile Evaluation Committee and the ICBM Scientific Advisory Committee. He was also a member of the influential Atomic Energy Commission in charge of all atomic energy development in the country. He played a key role alongside Bernard Schriever and Trevor Gardner in the design and development of the United States' first ICBM programs. At that time he was considered the nation's foremost expert on nuclear weaponry and the leading defense scientist at the U.S. Department of Defense.
Self-replication in the context of First universal common ancestor
The first universal common ancestor is proposed to have been a non-cellular entity that was the earliest organism with a genetic code capable of performing biological translation of RNA molecules to protein formation through peptides synthesis. Its descendants would include the last universal common ancestor (LUCA) and, therefore, all modern cells. FUCA would also be the ancestor of ancient sister lineages of LUCA with no direct modern descendants, but may have transferred genetic material horizontally into the genomes of early descendants of LUCA.
FUCA is thought to have been composed of progenotes, ancient biological systems that would have used RNA for their genome and self-replication. By comparison, LUCA would have had a complex metabolism and a DNA genome containing hundreds of genes grouped into several gene families.