Scientific research in the context of Laboratory mice


Scientific research in the context of Laboratory mice

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⭐ Core Definition: Scientific research

The scientific method is an empirical method for acquiring knowledge through careful observation, rigorous skepticism, hypothesis testing, and experimental validation. Developed from ancient and medieval practices, it acknowledges that cognitive assumptions can distort the interpretation of the observation. The scientific method has characterized science since at least the 17th century. Scientific inquiry includes creating a testable hypothesis through inductive reasoning, testing it through experiments and statistical analysis, and adjusting or discarding the hypothesis based on the results.

Although procedures vary across fields, the underlying process is often similar. In more detail: the scientific method involves making conjectures (hypothetical explanations), predicting the logical consequences of hypothesis, then carrying out experiments or empirical observations based on those predictions. A hypothesis is a conjecture based on knowledge obtained while seeking answers to the question. Hypotheses can be very specific or broad but must be falsifiable, implying that it is possible to identify a possible outcome of an experiment or observation that conflicts with predictions deduced from the hypothesis; otherwise, the hypothesis cannot be meaningfully tested.

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Scientific research in the context of Fundamental science

Basic research, also called pure research, fundamental research, basic science, or pure science, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques, which can be used to intervene and alter natural or other phenomena. Though often driven simply by curiosity, basic research often fuels the technological innovations of applied science. The two aims are often practiced simultaneously in coordinated research and development.

In addition to innovations, basic research serves to provide insights and public support of nature, possibly improving conservation efforts. Technological innovations may influence engineering concepts, such as the beak of a kingfisher influencing the design of a high-speed bullet train.

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Scientific research in the context of Data

Data (/ˈdtə/ DAY-tə, US also /ˈdætə/ DAT) are a collection of discrete or continuous values that convey information, describing the quantity, quality, fact, statistics, other basic units of meaning, or simply sequences of symbols that may be further interpreted formally. A datum is an individual value in a collection of data. Data are usually organized into structures such as tables that provide additional context and meaning, and may themselves be used as data in larger structures. Data may be used as variables in a computational process. Data may represent abstract ideas or concrete measurements.Data are commonly used in scientific research, economics, and virtually every other form of human organizational activity. Examples of data sets include price indices (such as the consumer price index), unemployment rates, literacy rates, and census data. In this context, data represent the raw facts and figures from which useful information can be extracted.

Data are collected using techniques such as measurement, observation, query, or analysis, and are typically represented as numbers or characters that may be further processed. Field data are data that are collected in an uncontrolled, in-situ environment. Experimental data are data that are generated in the course of a controlled scientific experiment. Data are analyzed using techniques such as calculation, reasoning, discussion, presentation, visualization, or other forms of post-analysis. Prior to analysis, raw data (or unprocessed data) is typically cleaned: Outliers are removed, and obvious instrument or data entry errors are corrected.

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Scientific research in the context of Religiosity and education

The relationship between the level of religiosity and the level of education has been studied since the second half of the 20th century.

The parameters of the two components are diverse: the "level of religiosity" remains a concept which is difficult to differentiate scientifically, while the "level of education" is easier to compile, such as official data on this topic, because data on education is publicly accessible in many countries.

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Scientific research in the context of Research station

Research stations are facilities where scientific investigation, collection, analysis and experimentation occurs. A research station is a facility that is built for the purpose of conducting scientific research. There are also many types of research stations including: biological field stations, space stations etc. Research station sites might include remote areas of the world, oceans, as well as outer space, such as the International Space Station. Biological research stations developed during a time of European colonization and imperialism where naturalists were employed to conduct observations on fauna and flora. Today, the discipline is represented by a number of organizations which span across multiple continents. Some examples include: the Organization of Biological Field Stations and the Organization for Tropical Studies.

Space stations were also developed over a number of decades through scientific analysis and writing, with the first design aspects of early space stations being introduced by Herman Potocnik in 1928. Since then, the construction and launch of space stations have been both national and international, collaborative efforts which have allowed different design philosophies to form key space stations such as the International Space Station (ISS). Similarly, stations in Antarctica are built to ensure that they are well insulated against the sub-zero temperatures of the exterior landscape with many redevelopments being required over the years to overcome issues associated with snowdrifts, accessibility and rusting.

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Scientific research in the context of Ultra-high vacuum

Ultra-high vacuum (often spelled ultrahigh in American English, UHV) is the vacuum regime characterised by pressure lower than about 1×10 torrs (1×10 mbar; 1×10 Pa). UHV conditions are created by pumping the gas out of a UHV chamber. At these low pressures the mean free path of a gas molecule is greater than approximately 40 km, so the gas is in free molecular flow, and gas molecules will collide with the chamber walls many times before colliding with each other. Almost all molecular interactions therefore take place on various surfaces in the chamber.

UHV conditions are integral to scientific research. Surface science experiments often require a chemically clean sample surface with the absence of any unwanted adsorbates. Surface analysis tools such as X-ray photoelectron spectroscopy and low energy ion scattering require UHV conditions for the transmission of electron or ion beams. For the same reason, beam pipes in particle accelerators such as the Large Hadron Collider are kept at UHV.

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Scientific research in the context of Geobiology

Geobiology is a field of scientific research that explores the interactions between the physical Earth and the biosphere. It is a relatively young field, and its borders are fluid. There is considerable overlap with the fields of ecology, evolutionary biology, microbiology, paleontology, and particularly soil science and biogeochemistry. Geobiology applies the principles and methods of biology, geology, and soil science to the study of the ancient history of the co-evolution of life and Earth as well as the role of life in the modern world. Geobiologic studies tend to be focused on microorganisms, and on the role that life plays in altering the chemical and physical environment of the pedosphere, which exists at the intersection of the lithosphere, atmosphere, hydrosphere and/or cryosphere. It differs from biogeochemistry in that the focus is on processes and organisms over space and time rather than on global chemical cycles.

Geobiological research synthesizes the geologic record with modern biologic studies. It deals with process - how organisms affect the Earth and vice versa - as well as history - how the Earth and life have changed together. Much research is grounded in the search for fundamental understanding, but geobiology can also be applied, as in the case of microbes that clean up oil spills.

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Scientific research in the context of Experimental data

Experimental data in science and engineering is data produced by a measurement, test method, experimental design or quasi-experimental design. In clinical research any data produced are the result of a clinical trial. Experimental data may be qualitative or quantitative, each being appropriate for different investigations.

Generally speaking, qualitative data are considered more descriptive and can be subjective in comparison to having a continuous measurement scale that produces numbers. Whereas quantitative data are gathered in a manner that is normally experimentally repeatable, qualitative information is usually more closely related to phenomenal meaning and is, therefore, subject to interpretation by individual observers.

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Scientific research in the context of Radio control

Radio control (often abbreviated to RC) is the use of control signals transmitted by radio to remotely operate a device. Examples of simple radio control systems are garage door openers and keyless entry systems for vehicles, in which a small handheld radio transmitter unlocks or opens doors. Radio control is also used for control of model vehicles from a hand-held radio transmitter. Industrial, military, and scientific research organizations make use of radio-controlled vehicles as well. A rapidly growing application is control of unmanned aerial vehicles (UAVs or drones) for both civilian and military uses, although these have more sophisticated control systems than traditional applications.

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Scientific research in the context of SRI International

SRI International (SRI; originally the Stanford Research Institute) is a nonprofit scientific research institute and organization headquartered in Menlo Park, California, United States. It was established in 1946 by trustees of Stanford University to serve as a center of innovation to support economic development in the region.

The organization was founded as the Stanford Research Institute in 1946, formally separated from Stanford University in 1970, and became known as SRI International in 1977. SRI performs client-sponsored research and development for government agencies, commercial businesses, and private foundations. It also licenses its technologies, forms strategic partnerships, sells products, and creates spin-off companies. SRI's headquarters are located near the Stanford University campus.

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Scientific research in the context of Human Genome Project

The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint. It started in 1990 and was completed in 2003. It was the world's largest collaborative biological project. Planning for the project began in 1984 by the US government, and it officially launched in 1990. It was declared complete on 14 April 2003, and included about 92% of the genome. Level "complete genome" was achieved in May 2021, with only 0.3% of the bases covered by potential issues. The final gapless assembly was finished in January 2022.

Funding came from the US government through the National Institutes of Health (NIH) as well as numerous other groups from around the world. A parallel project was conducted outside the government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centres in the United States, the United Kingdom, Japan, France, Germany, and China, working in the International Human Genome Sequencing Consortium (IHGSC).

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Scientific research in the context of Laboratory rat

Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice, rats have served as an important animal model for research in psychology and biomedical science, and "lab rat" is commonly used as an idiom for a test subject.

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Scientific research in the context of Sociology of scientific ignorance

The sociology of scientific ignorance (SSI) is the study of ignorance in and of science. The most common way is to see ignorance as something relevant, rather than simply lack of knowledge. There are two distinct areas in which SSI is being studied: some focus on ignorance in scientific research, whereas others focus on public ignorance of science. Sociology of scientific ignorance is a complementary field to the sociology of scientific knowledge (SSK).

When studying ignorance in scientific research, the common standpoint is that ignorance can be used as a tool in science. An example of this is blackboxing, which is the notion that it can be beneficial to hide the internal parts of a system, and only make the input and output visible to the user.

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Scientific research in the context of Technical report

A technical report (also scientific report) is a document that describes the process, progress, or results of technical or scientific research or the state of a technical or scientific research problem. It might also include recommendations and conclusions of the research. Unlike other scientific literature, such as scientific journals and the proceedings of some academic conferences, technical reports rarely undergo comprehensive independent peer review before publication. They may be considered as grey literature. Where there is a review process, it is often limited to within the originating organization. Similarly, there are no formal publishing procedures for such reports, except where established locally.

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