Santiago de Cuba Province in the context of Pico Turquino

The 1900 Galveston hurricane, also known as the Great Galveston hurricane and the Galveston Flood, and known regionally as the Great Storm of 1900 or the 1900 Storm, was a catastrophic tropical cyclone that became the deadliest natural disaster in the history of the United States. The strongest storm of the 1900 Atlantic hurricane season, it left between 6,000 and 12,000 fatalities in the United States; the number most cited in official reports is 8,000. Most of these deaths occurred in and near Galveston, Texas, after the storm surge inundated the coastline and the island city with 8 to 12 ft (2.4 to 3.7 m) of water. As of 2025, it remains the fourth deadliest Atlantic hurricane on record, behind Hurricane Fifi of 1974. In addition to the number killed, the storm destroyed about 7,000 buildings of all uses in Galveston, which included 3,636 demolished homes; every dwelling in the city suffered some degree of damage. The hurricane left approximately 10,000 people in the city homeless, out of a total population of fewer than 38,000. The disaster ended the Golden Era of Galveston. The hurricane alarmed potential investors, who turned to Houston instead. In response to the storm, three engineers designed and oversaw plans to raise the Gulf of Mexico shoreline of Galveston Island by 17 ft (5.2 m) and erect a 10 mi (16 km) seawall.

On August 27, 1900, a ship east of the Windward Islands detected a tropical cyclone, the first observed that year. The system proceeded to move steadily west-northwestward and entered the northeastern Caribbean on August 30. It made landfall in the Dominican Republic as a weak tropical storm on September 2. It weakened slightly while crossing Hispaniola, before re-emerging into the Caribbean Sea later that day. On September 3, the cyclone struck modern-day Santiago de Cuba Province and then slowly drifted along the southern coast of Cuba. Upon reaching the Gulf of Mexico on September 6, the storm strengthened into a hurricane. Significant intensification followed and the system peaked as a Category 4 hurricane with maximum sustained winds of 145 mph (235 km/h) on September 8. Early on the next day, it made landfall to the south of Houston. The cyclone weakened quickly after moving inland and fell to tropical storm intensity late on September 9. The storm turned east-northeastward and became extratropical over Iowa on September 11. The extratropical system strengthened while accelerating across the Midwestern United States, New England, and Eastern Canada before reaching the Gulf of Saint Lawrence on September 13. After striking Newfoundland later that day, the extratropical storm entered the far North Atlantic Ocean and weakened, with the remnants last observed near Iceland on September 15.

The Sierra Maestra is a mountain range that runs westward across the south of the old Oriente Province in southeast Cuba, rising abruptly from the coast. The range falls mainly within the Santiago de Cuba and in Granma Provinces. Some view it as a series of connecting ranges (Vela, Santa Catalina, Quemado Grande, Daña Mariana), which join with others to the west. At 1,974 m (6,476 ft), Pico Turquino is the range's – and the country's – highest point. The area is rich in minerals, especially copper, manganese, chromium, and iron.

Santiago de Cuba is the second-largest city in Cuba and the capital city of Santiago de Cuba Province. It lies in the southeastern area of the island, some 870 km (540 mi) southeast of the Cuban capital of Havana.

The municipality extends over 1,023.8 km (395.3 sq mi), and contains the communities of Antonio Maceo, Bravo, Castillo Duany, Daiquirí, El Caney, El Cobre, El Cristo, Guilera, Leyte Vidal, Moncada and Siboney.

Oriente ([oˈɾjente], "East") was the easternmost province of Cuba until 1976. The term "Oriente" is still used to refer to the eastern part of the country, which currently is divided into five different provinces.

The origins of Oriente lie in the 1607 division of Cuba into a western and eastern administration. The eastern part was governed from Santiago de Cuba and it was subordinate to the national government in Havana. In 1807, Cuba was divided into three departamentos: Occidental, Central and Oriental. This arrangement lasted until 1851, when the central department was merged back into the West. In 1878, Cuba was divided into six provinces. Oriente remained intact but was officially renamed to Santiago de Cuba Province until the name was reverted to Oriente in 1905. Fidel and Raúl Castro were born in a small town in Oriente province (Birán). The province was split in 1976 into five different provinces: Las Tunas Province, Granma Province, Holguín Province, Santiago de Cuba Province, and Guantánamo Province. This administrative change was proclaimed by Cuban Law Number 1304 of July 3, 1976, and remains in place to this day.