De Stella Nova in Pede Serpentarii (On the New Star in the Foot of the Serpent Handler), generally known as De Stella Nova was a book written by Johannes Kepler between 1605 and 1606, when the book was published in Prague.
Kepler wrote the book following the appearance of the supernova SN 1604, also known as Kepler's Supernova. This star appeared in the constellation Ophiuchus, the Greek (Ὀφιοῦχος Ophioukhos) "serpent-bearer" which is also known in Latin as Serpentarius.