Royal Proclamation of 1763 in the context of "Westward expansion"

The Southern Colonies within British America consisted of the Province of Maryland, the Colony of Virginia, the Province of Carolina (in 1712 split into North and South Carolina), and the Province of Georgia. In 1763, the newly created colonies of East Florida and West Florida were added to the Southern Colonies by Great Britain until the Spanish Empire took back Florida. These colonies were the historical core of what became the Southern United States, or "Dixie". They were located south of the Middle Colonies, although Virginia and Maryland (located on the expansive Chesapeake Bay in the Upper South) were also called the Chesapeake Colonies.

The Southern Colonies were overwhelmingly rural, with large agricultural operations, which made extensive use of slavery and indentured servitude. During a period of civil unrest, Bacon's Rebellion shaped the way that servitude and slavery worked in the South. After a series of attacks on the Susquehannock, attacks that ensued after the group of natives burnt one of Bacon's farms, Bacon's arrest, along with other arrest warrants, were issued by Governor Berkely, for attacking the natives without his permission. Bacon avoided detainment, though, and then burnt Jamestown, in response to the governor previously denying him land in fear of native attacks. Bacon hadn't believed his policies were entirely conventional, saying that they didn't ensure protection to the English settlers, as well as the exclusion of Bacon from Berkeley's social clubs and friend groups. The rebellion dissolved some time in 1676, following Charles II's initial sending of troops to restore order in the colony. This rebellion influenced the view of the Africans, helping create a completely African servitude and workforce in the Chesapeake Colonies, alleviating primarily White servitude, a working class that could be repugnant at times through disobedience and mischief. This also helped racial superiority in white regions, helping the poor and wealthy white people feel almost equal. It diminished alliances between white and black people, as had happened in Bacon's Rebellion.

The United States of America was formed after thirteen British colonies in North America declared independence from the British Empire on July 4, 1776. In the Lee Resolution, passed by the Second Continental Congress two days prior, the colonies resolved that they were free and independent states. The union was formalized in the Articles of Confederation, which came into force on March 1, 1781, after being ratified by all 13 states. Their independence was recognized by Great Britain in the Treaty of Paris of 1783, which concluded the American Revolutionary War. This effectively doubled the size of the colonies, now able to stretch west past the Proclamation Line to the Mississippi River. This land was organized into territories and then states, though there remained some conflict with the sea-to-sea grants claimed by some of the original colonies. In time, these grants were ceded to the federal government.

The first great expansion of the country came with the Louisiana Purchase of 1803, which doubled the country's territory, although the southeastern border with Spanish Florida was the subject of much dispute until it and Spanish claims to the Oregon Country were ceded to the US in 1821. The Oregon Country gave the United States access to the Pacific Ocean, though it was shared for a time with the United Kingdom. The annexation of the Republic of Texas in 1845 led directly to the Mexican–American War, after which the victorious United States obtained the northern half of Mexico's territory, including what was quickly made the state of California.

The Province of Quebec (French: Province de Québec) was a colony in British North America which comprised the former French colony of Canada. It was established by the Kingdom of Great Britain in 1763, following the conquest of New France by British forces during the Seven Years' War. As part of the 1763 Treaty of Paris, France gave up its claim to the colony; it instead negotiated to keep the small profitable island of Guadeloupe.

Following the Royal Proclamation of 1763, Canada was renamed the Province of Quebec, and from 1774 extended from the coast of Labrador on the Atlantic Ocean, southwest through the Saint Lawrence River Valley to the Great Lakes and beyond to the confluence of the Ohio and Mississippi Rivers in the Illinois Country. Portions of its southwest, those areas south of the Great Lakes, were later ceded to the newly established United States in the 1783 Treaty of Paris at the conclusion of the American Revolution; although the British maintained a military presence there until 1796 and the Jay Treaty. In 1791, the territory north of the Great Lakes was reorganised and divided into Lower Canada and Upper Canada.

Starting with the 1763 Treaty of Paris, New France, of which the colony of Canada was a part, formally became a part of the British Empire. The Royal Proclamation of 1763 enlarged the colony of Canada under the name of the Province of Quebec, which with the Constitutional Act 1791 became known as the Canadas. With the Act of Union 1840, Upper and Lower Canada were joined to become the Province of Canada.

By the 1860s, interest developed in forming a new federation between the Canadas and the other British colonies of British North America, that led to Confederation in 1867. A number of other British colonies that are today part of Canada, such as Newfoundland and British Columbia, and large territories such as Rupert's Land, initially remained outside the newly formed federation.

Daniel Boone (November 2 [O.S. October 22], 1734 – September 26, 1820) was an American pioneer and frontiersman whose exploits made him one of the first folk heroes of the United States. He became famous for his exploration and settlement of Kentucky, which was then beyond the western borders of the Thirteen Colonies. In 1775, Boone founded the Wilderness Road through the Cumberland Gap and into Kentucky, in the face of resistance from Native Americans. He founded Boonesborough, one of the first English-speaking settlements west of the Appalachian Mountains. By the end of the 18th century, more than 200,000 people had entered Kentucky by following the route marked by Boone.

He served as a militia officer during the Revolutionary War (1775–1783), which in Kentucky was fought primarily between American settlers and British-allied Indians. In 1778, Boone was captured by the Shawnee and was, according to legend, adopted by the Shawnee Chief and given the name "Sheltowee", or Big Turtle. After months of living with the Shawnee, Boone escaped. He was elected to the first of his three terms in the Virginia General Assembly during the war and fought in the Battle of Blue Licks in 1782, one of the last battles of the American Revolution. He worked as a surveyor and merchant after the war, but went deep into debt as a Kentucky land speculator. He resettled in Missouri in 1799, where he spent most of the last two decades of his life, frustrated with legal problems resulting from his land claims.

The Northwest Indian War was an armed conflict for control of the Northwest Territory between the United States and a loose confederation of Native American peoples who called themselves the United Indian Nations but are better known today as the Northwestern Confederacy. The United States Army considers the conflict to be the first of the American Indian Wars.

Following centuries of conflict involving Native Americans and Europeans for control of the region, the lands comprising the Northwest Territory were ceded by Great Britain to the newly formed United States in the 1783 Treaty of Paris. The treaty used the Great Lakes as a border between British North America and the US, and led to the Americans assuming control over the Ohio Country and Illinois Country, which had previously been prohibited to American settlement. As US settlers moved into the Northwest Territory, they were resisted by local Native Americans, and a Huron-led confederacy was formed in 1785 to resist American expansion onto their lands.