Sistine Chapel in the context of "Commissioning of the Twelve Apostles"

Pope Julius II (Latin: Iulius II; Italian: Giulio II; born Giuliano della Rovere; 5 December 1443 – 21 February 1513) was head of the Catholic Church and ruler of the Papal States from 1503 to his death, in February 1513. Nicknamed the Warrior Pope, the Battle Pope or the Fearsome Pope, it is often speculated that he had chosen his papal name not in honor of Pope Julius I but in emulation of Julius Caesar. One of the most powerful and influential popes, Julius II was a central figure of the High Renaissance and left a significant cultural and political legacy. As a result of his policies during the Italian Wars, the Papal States increased their power and centralization, and the office of the papacy continued to be crucial, diplomatically and politically, during the entirety of the 16th century in Italy and Europe.

In 1506, Julius II established the Vatican Museums and initiated the rebuilding of the St. Peter's Basilica. The same year he organized the famous Swiss Guard for his personal protection and commanded a successful campaign in Romagna against local lords. The interests of Julius II lay also in the New World, as he ratified the Treaty of Tordesillas, establishing the first bishoprics in the Americas and beginning the Catholicization of Latin America. In 1508, he commissioned the Raphael Rooms and Michelangelo's paintings in the Sistine Chapel.

The chronology of the Bible is an elaborate system of lifespans, "generations", and other means by which the Masoretic Hebrew Bible (the text of the Bible most commonly in use today) measures the passage of events from the creation to around 164 BCE (the year of the re-dedication of the Second Temple). It was theological in intent, not historical in the modern sense, and functions as an implied prophecy whose key lies in the identification of the final event. The passage of time is measured initially by adding the ages of the Patriarchs at the birth of their firstborn sons, later through express statements, and later still by the synchronised reigns of the kings of Israel and Judah.

The chronology is highly schematic, marking out a world cycle of 4,000 years. The Exodus takes place in the year A.M. 2666 (Anno Mundi, years since the creation of the world), exactly two-thirds of the way through the 4,000-year period: the construction of Solomon's Temple commences 480 years afterward—12 generations of 40 years each—and 430 years pass between the building of Solomon's Temple and its destruction during the siege of Jerusalem. The 50 years between the destruction of the Temple and the "Decree of Cyrus" and end of the Babylonian Exile, added to the 430 years for which the Temple stood, produces another symmetrical period of 480 years. The 374 years between the Edict of Cyrus and the re-dedication of the Second Temple by the Maccabees complete the 4,000-year cycle.

The Apostolic Palace is the official residence of the Pope, the head of the Catholic Church, located in Vatican City. It is also known as the Papal Palace, the Palace of the Vatican and the Vatican Palace. The Vatican itself refers to the building as the Palace of Sixtus V, in honor of Pope Sixtus V, who built most of the present form of the palace.

The building contains the papal apartments, various offices of the Catholic Church and the Holy See, private and public chapels, the Vatican Museums, and the Vatican Library, including the Sistine Chapel, Raphael Rooms, and the Borgia Apartments. Tourists can see this part of the palace, but other parts, such as the Sala Regia (Regal Room) and Cappella Paolina, had long been closed to tourists, though the Sala Regia allowed occasional tourism by 2019. The Scala Regia (Regal Staircase) can be viewed from one end and used to enter the Sala Regia. The Cappella Paolina remains closed to tourists.

Alessandro di Mariano di Vanni Filipepi (c. 1445 – May 17, 1510), better known as Sandro Botticelli (/ˌbɒtɪˈtʃɛli/ BOT-ih-CHEL-ee; Italian: [ˈsandro bottiˈtʃɛlli]) or simply Botticelli, was an Italian painter of the Early Renaissance. Botticelli's posthumous reputation suffered until the late 19th century, when he was rediscovered by the Pre-Raphaelites who stimulated a reappraisal of his work. Since then, his paintings have been seen to represent the linear grace of late Italian Gothic and some Early Renaissance painting, even though they date from the latter half of the Italian Renaissance period.

In addition to the mythological subjects for which he is best known today, Botticelli painted a wide range of religious subjects (including dozens of renditions of the Madonna and Child, many in the round tondo shape) and also some portraits. His best-known works are The Birth of Venus and Primavera, both in the Uffizi in Florence, which holds many of Botticelli's works. Botticelli lived all his life in the same neighbourhood of Florence; his only significant times elsewhere were the months he spent painting in Pisa in 1474 and the Sistine Chapel in Rome in 1481–82.

The Sala Regia (Regal Room) is a state hall in the Apostolic Palace in Vatican City.

Although not intended as such, this broad room is really an antechamber to the Sistine Chapel. It also connects to the Pauline Chapel and is reached by the long staircase known as the Scala Regia. To the left of the entrance formerly stood the papal throne, which is now at the opposite side before the door leading to the Pauline Chapel.

The Sistine Chapel ceiling (Italian: Soffitto della Cappella Sistina), painted in fresco by Michelangelo between 1508 and 1512, is a cornerstone work of High Renaissance art.

The Sistine Chapel is the large papal chapel built within the Vatican between 1477 and 1480 by Pope Sixtus IV, for whom the chapel is named. The ceiling was painted at the commission of Pope Julius II.

The Last Judgment (Italian: Il Giudizio Universale) is a fresco by the Italian Renaissance painter Michelangelo covering the whole altar wall of the Sistine Chapel in Vatican City. It is a depiction of the Second Coming of Christ and the final and eternal judgment by God of all humanity. The dead rise and descend to their fates, as judged by Christ who is surrounded by prominent saints. Altogether there are over 300 figures, with nearly all the males and angels originally shown as nudes; many were later partly covered up by painted draperies, of which some remain after recent cleaning and restoration.

The work took over four years to complete between 1536 and 1541 (preparation of the altar wall began in 1535). Michelangelo began working on it 25 years after finishing the Sistine Chapel ceiling, and was nearly 67 at its completion. He had originally accepted the commission from Pope Clement VII, but it was completed under Pope Paul III whose stronger reforming views probably affected the final treatment.

The Vatican Museums (Italian: Musei Vaticani; Latin: Musea Vaticana) are the public museums of the Vatican City. They display works from the immense collection amassed by the Catholic Church and the papacy throughout the centuries, including several of the best-known Roman sculptures and most important masterpieces of Renaissance art in the world. The museums contain roughly 70,000 works, of which 20,000 are on display, and currently employ 640 people who work in 40 different administrative, scholarly, and restoration departments.

Pope Julius II founded the museums in the early 16th century. The Sistine Chapel, with its ceiling and altar wall decorated by Michelangelo, and the Stanze di Raffaello (decorated by Raphael) are on the visitor route through the Vatican Museums, considered among the most canonical and distinctive works of Western and European art.