Khushab District (Punjabi: ضِلع خُوشاب) is a district in the province of Punjab, Pakistan, with its administrative capital in Jauharabad. The district is named after the historical city of Khushab.
The district consists of four tehsils: Khushab, Noorpur Thal, Quaidabad and Naushera. Khushab is home to the Heavy Water and Natural Uranium Research Reactor, part of Pakistan's Special Weapons Program.District Khushab shares boundaries with the districts of Sargodha, Jhelum, Chakwal, Mianwali, Bhakkar and Jhang.