Prenatal development in the context of Development of the breasts

The Socratic method (also known as Socratic debate, the Socratic dialectic, or the method of Elenchus) is a form of argumentative dialogue in which an individual probes a conversation partner on a topic with questions and clarifications, until the partner is pressed to come to a conclusion on their own, or else their reasoning breaks down and they are forced to admit ignorance. Socratic dialogues between characters employing this method feature in many of the works of the ancient Greek philosopher Plato, where a fictionalized version of his real-life teacher Socrates debates various philosophical issues with a partner.

In Plato's dialogue "Theaetetus", Socrates describes his method as a form of "midwifery" because it is employed to help his interlocutors develop their understanding in a way analogous to a child developing in the womb. The Socratic method begins with commonly held beliefs and scrutinizes them by way of questioning to determine their internal consistency and their coherence with other beliefs and so to bring everyone closer to the truth.

Gestation is the period of development during the carrying of an embryo, and later fetus, inside viviparous animals (the embryo develops within the parent). It is typical for mammals, but also occurs for some non-mammals. Mammals during pregnancy can have one or more gestations at the same time, for example in a multiple birth.

The time interval of a gestation is called the gestation period. In obstetrics, gestational age refers to the time since the onset of the last menses, which on average is fertilization age plus two weeks.

A fetus or foetus (/ˈfiːtəs/; pl.: fetuses, foetuses, rarely feti or foeti) is the unborn offspring of a viviparous animal that develops from an embryo. Following the embryonic stage, the fetal stage of development takes place. Prenatal development is a continuum, with no clear defining feature distinguishing an embryo from a fetus. However, in general a fetus is characterized by the presence of all the major body organs, though they will not yet be fully developed and functional, and some may not yet be situated in their final anatomical location.

In human prenatal development, fetal development begins from the ninth week after fertilization (which is the eleventh week of gestational age) and continues until the birth of a newborn.

The cerebrum (pl.: cerebra), telencephalon or endbrain is the largest part of the brain, containing the cerebral cortex (of the two cerebral hemispheres) as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system. The cerebrum develops prenatally from the forebrain (prosencephalon). In mammals, the dorsal telencephalon, or pallium, develops into the cerebral cortex, and the ventral telencephalon, or subpallium, becomes the basal ganglia. The cerebrum is also divided into approximately symmetric left and right cerebral hemispheres.

With the assistance of the cerebellum, the cerebrum controls all voluntary actions in the human body.

The uterus (from Latin uterus, pl.: uteri or uteruses) or womb (/wuːm/) is the organ in the reproductive system of most female mammals, including humans, that accommodates the embryonic and fetal development of one or more fertilized eggs until birth. The uterus is a hormone-responsive sex organ that contains glands in its lining that secrete uterine milk for embryonic nourishment. (The term uterus is also applied to analogous structures in some non-mammalian animals.)

In humans, the lower end of the uterus is a narrow part known as the isthmus that connects to the cervix, the anterior gateway leading to the vagina. The upper end, the body of the uterus, is connected to the fallopian tubes at the uterine horns; the rounded part, the fundus, is above the openings to the fallopian tubes. The connection of the uterine cavity with a fallopian tube is called the uterotubal junction. The fertilized egg is carried to the uterus along the fallopian tube. It will have divided on its journey to form a blastocyst that will implant itself into the lining of the uterus – the endometrium, where it will receive nutrients and develop into the embryo proper, and later fetus, for the duration of the pregnancy.

Intrauterine growth restriction (IUGR), or fetal growth restriction, is the poor growth of a fetus while in the womb during pregnancy. IUGR is defined by clinical features of malnutrition and evidence of reduced growth regardless of an infant's birth weight percentile. The causes of IUGR are broad and may involve maternal, fetal, or placental complications.

At least 60% of the 4 million neonatal deaths that occur worldwide every year are associated with low birth weight, caused by intrauterine growth restriction (IUGR), preterm delivery, and genetic abnormalities, demonstrating that under-nutrition is already a leading health problem at birth.

In developmental biology, animal embryonic development, also known as animal embryogenesis, is the developmental stage of an animal embryo. Embryonic development starts with the fertilization of an egg cell (ovum) by a sperm cell (spermatozoon). Once fertilized, the ovum becomes a single diploid cell known as a zygote. The zygote undergoes mitotic divisions with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of a multicellular embryo after passing through an organizational checkpoint during mid-embryogenesis. In mammals, the term refers chiefly to the early stages of prenatal development, whereas the terms fetus and fetal development describe later stages.

The main stages of animal embryonic development are as follows:

Homosexuality is romantic attraction, sexual attraction, or sexual behavior between people of the same sex or gender. It also denotes identity based on attraction, related behavior, and community affiliation.

Along with bisexuality and heterosexuality, homosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Although no single theory on the cause of sexual orientation has yet gained widespread support, scientists favor biological theories. There is considerably more evidence supporting nonsocial, biological causes of sexual orientation than social ones, especially for males. A major hypothesis implicates the prenatal environment, specifically the organizational effects of hormones on the fetal brain. There is no substantive evidence which suggests parenting or early childhood experiences play a role in developing a sexual orientation. Scientific research shows that homosexuality is a natural and normal variation in human sexuality and is not in and of itself a source of negative psychological effects. Major mental health organizations overwhelmingly reject conversion therapy as ineffective, scientifically unsupported and potentially harmful.

A cleft lip contains an opening in the upper lip that may extend into the nose. The opening may be on one side, both sides, or in the middle. A cleft palate occurs when the palate (the roof of the mouth) contains an opening into the nose. The term orofacial cleft refers to either condition or to both occurring together. These disorders can result in feeding problems, speech problems, hearing problems, and frequent ear infections. Less than half the time the condition is associated with other disorders.

Cleft lip and palate are the result of tissues of the face not joining properly during development. As such, they are a type of birth defect. The cause is unknown in most cases. Risk factors include smoking during pregnancy, diabetes, obesity, an older mother, and certain medications (such as some used to treat seizures). Cleft lip and cleft palate can often be diagnosed during pregnancy with an ultrasound exam.

In placental mammals, the umbilical cord (also called the navel string, birth cord or funiculus umbilicalis) is a conduit between the developing embryo or fetus and the placenta. During prenatal development, the umbilical cord is physiologically and genetically part of the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta. Conversely, the fetal heart pumps low-oxygen, nutrient-depleted blood through the umbilical arteries back to the placenta.

Autism, also known as autism spectrum disorder (ASD), is a condition characterized by differences or difficulties in social communication and interaction, a need or strong preference for predictability and routine, sensory processing differences, focused interests, and repetitive behaviors. Characteristics of autism are present from early childhood and the condition typically persists throughout life. Autism is classified as a neurodevelopmental disorder, and a formal diagnosis requires professional assessment that these characteristics cause significant challenges in daily life beyond what would be expected given a person's age and social environment. Because autism is a spectrum disorder, presentations vary and support needs range from minimal to the person being non-speaking or needing 24-hour care.

Autism diagnoses have risen since the 1990s, largely because of broader diagnostic criteria, greater awareness, and wider access to assessment. Changing social demands may also play a role. The World Health Organization estimates that about 1 in 100 children were diagnosed between 2012 and 2021, noting an increasing trend. Surveillance studies suggest a similar share of the adult population would meet diagnostic criteria if formally assessed. This rise has fueled anti-vaccine activists' disproven claim that vaccines cause autism, based on a fraudulent 1998 study that was later retracted. Autism is highly heritable and involves many genes, while environmental factors appear to play a smaller, mainly prenatal role. Boys are diagnosed several times more often than girls, and conditions such as anxiety, depression, attention deficit hyperactivity disorder (ADHD), epilepsy, and intellectual disability are more common among autistic people.

Gyrification is the process of forming the characteristic folds of the cerebral cortex. The peak of such a fold is called a gyrus (pl. gyri), and its trough is called a sulcus (pl. sulci). The neurons of the cerebral cortex reside in a thin layer of gray matter, only 2–4 mm thick, at the surface of the brain. Much of the interior volume is occupied by white matter, which consists of long axonal projections to and from the cortical neurons residing near the surface. Gyrification allows a larger cortical surface area, and hence greater cognitive functionality to fit inside a smaller cranium.

In most mammals, gyrification begins during fetal development. Primates, cetaceans, and ungulates have extensive cortical gyri, with a few species exceptions, while small rodents such as the rat, and mouse have none. Gyrification in some animals, for example the ferret, continues well into postnatal life.

The ovary (from Latin ōvārium 'egg') is a gonad in the female reproductive system that produces ova; when released, an ovum travels through the fallopian tube/oviduct into the uterus. There is an ovary on the left and the right side of the body. The ovaries are endocrine glands, secreting various hormones that play a role in the menstrual cycle and fertility. The ovary progresses through many stages beginning in the prenatal period through menopause.

Neonatal infections are infections of the neonate (newborn) acquired during prenatal development or within the first four weeks of life. Neonatal infections may be contracted by mother to child transmission, in the birth canal during childbirth, or after birth. Neonatal infections may present soon after delivery, or take several weeks to show symptoms. Some neonatal infections such as HIV, hepatitis B, and malaria do not become apparent until much later. Signs and symptoms of infection may include respiratory distress, temperature instability, irritability, poor feeding, failure to thrive, persistent crying and skin rashes.

Risk factors include previous maternal infection, preterm delivery (< 37 weeks gestation) and premature rupture of membranes (breakage of the amniotic sac) which substantially increases the risk of neonatal sepsis by allowing passage for bacteria to enter the womb prior to the birth of the infant. Preterm or low birth weight neonates are more vulnerable to neonatal infection. While preterm neonates are at a particularly high risk, all neonates can develop infection. Maternal screening for intrapartum infections reduce the risk of neonatal infection. Pregnant women may receive intrapartum antibiotic prophylaxis for prevention of neonatal infection.